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Synthesis of artificial dental enamel by an elastin-like polypeptide assisted biomimetic approach
- Source :
- Journal of materials chemistry. B. 6(5)
- Publication Year :
- 2020
-
Abstract
- Teeth are important for our life, and enamel, as the outermost layer of the tooth, plays a key role in maintaining the function and health of the tooth. Regeneration of acid eroded enamel is a big challenge due to the lack of living cells in the enamel. Here, we propose a novel way to chemically synthesize the enamel structure by mimicking the interaction of amorphous calcium phosphate (ACP) and acidic proteins during the formation of natural enamel. The process includes the formation of ACP in situ by acid etching and then the formation of a Ca-rich polypeptide-ACP complex on acid etched enamel apatite crystals, the oriented nucleation and growth of apatite nano-crystals along the acid etched enamel apatite crystals, and infiltration of a regenerated enamel apatite structure with dental resin. The synthesized enamel reveals not only excellent mechanical properties, which are highly close to those of original natural enamel, but also reveals high chemical stability against acid erosion. This innovative method may create potential applications of the functional artificial enamel for repairing damaged tooth enamel.
- Subjects :
- Biomedical Engineering
02 engineering and technology
010402 general chemistry
01 natural sciences
Apatite
stomatognathic system
medicine
General Materials Science
Amorphous calcium phosphate
Enamel paint
biology
Acid etching
Chemistry
Dental enamel
Acid erosion
General Chemistry
General Medicine
021001 nanoscience & nanotechnology
medicine.disease
Tooth enamel
0104 chemical sciences
stomatognathic diseases
medicine.anatomical_structure
Chemical engineering
visual_art
visual_art.visual_art_medium
biology.protein
0210 nano-technology
Elastin
Subjects
Details
- ISSN :
- 20507518
- Volume :
- 6
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Journal of materials chemistry. B
- Accession number :
- edsair.doi.dedup.....c7cfd5c653a561ea9236aba4501fa6b5