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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
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- Nature Communications, Lu, Y, Day, F R, Gustafsson, S, Buchkovich, M L, Na, J, Bataille, V, Cousminer, D L, Dastani, Z, Drong, A W, Esko, T, Evans, D M, Falchi, M, Feitosa, M F, Ferreira, T, Hedman, Å K, Haring, R, Hysi, P G, Iles, M M, Justice, A E, Kanoni, S, Lagou, V, Li, R, Li, X, Locke, A, Lu, C, Mägi, R, Perry, J R B, Pers, T H, Qi, Q, Sanna, M, Schmidt, E M, Scott, W R, Shungin, D, Teumer, A, Vinkhuyzen, A A E, Walker, R W, Westra, H-J, Zhang, M, Zhang, W, Zhao, J H, Zhu, Z, Afzal, U, Ahluwalia, T S, Bakker, S J L, Bellis, C, Bonnefond, A, Borodulin, K, Buchman, A S, Cederholm, T, Choh, A C, Choi, H J, Curran, J E, de Groot, L C P G M, De Jager, P L, Dhonukshe-Rutten, R A M, Enneman, A W, Eury, E, Evans, D S, Forsen, T, Friedrich, N, Fumeron, F, Garcia, M E, Gärtner, S, Han, B-G, Havulinna, A S, Hayward, C, Hernandez, D, Hillege, H, Ittermann, T, Kent, J W, Kolcic, I, Laatikainen, T, Lahti, J, Leach, I M, Lee, C G, Lee, J-Y, Liu, T, Liu, Y, Lobbens, S, Loh, M, Lyytikaïnen, L-P, Medina-Gómez, C, Michaëlsson, K, Nalls, M, Nielson, C M, Oozageer, L, Pascoe, L, Paternoster, L, Polašek, O, Ripatti, S, Sarzynski, M A, Shin, C S, Narančić, N S, Spira, D, Srikanth, P, Steinhagen-Thiessen, E, Sung, Y J, Swart, K M A, Taittonen, L, Tanaka, T, Tikkanen, E, van der Velde, N, van Schoor, N M, Verweij, N, Wright, A F, Yu, L, Zmuda, J M, Eklund, N, Forrester, T, Grarup, N, Jackson, A U, Kristiansson, K, Kuulasmaa, T, Kuusisto, J, Lichtner, P, Luan, J, Mahajan, A, Männistö, S, Palmer, C D, Ried, J S, Scott, R A, Stancáková, A, Wagner, P J, Demirkan, A, Döring, A, Gudnason, V, Kiel, D P, Kühnel, B, Mangino, M, McKnight, B, Menni, C, O'Connell, J R, Oostra, B A, Shuldiner, A R, Song, K, Vandenput, L, van Duijn, C M, Vollenweider, P, White, C C, Boehnke, M, Böttcher, Y, Cooper, R S, Forouhi, N G, Gieger, C, Grallert, H, Hingorani, A, Jørgensen, T, Jousilahti, P, Kivimaki, M, Kumari, M, Laakso, M, Langenberg, C, Linneberg, A, Luke, A, McKenzie, C A, Palotie, A, Pedersen, O, Peters, A, Strauch, K, Tayo, B O, Wareham, N J, Bennett, D A, Bertram, L, Blangero, J, Blüher, M, Bouchard, C, Campbell, H, Cho, N H, Cummings, S R, Czerwinski, S A, Demuth, I, Eckardt, R, Eriksson, J G, Ferrucci, L, Franco, O H, Froguel, P, Gansevoort, R T, Hansen, T, Harris, T B, Hastie, N, Heliövaara, M, Hofman, A, Jordan, J M, Jula, A, Kähönen, M, Kajantie, E, Knekt, P B, Koskinen, S, Kovacs, P, Lehtimäki, T, Lind, L, Liu, Y, Orwoll, E S, Osmond, C, Perola, M, Pérusse, L, Raitakari, O T, Rankinen, T, Rao, D C, Rice, T K, Rivadeneira, F, Rudan, I, Salomaa, V, Sørensen, T I A, Stumvoll, M, Tönjes, A, Towne, B, Tranah, G J, Tremblay, A, Uitterlinden, A G, van der Harst, P, Vartiainen, E, Viikari, J S, Vitart, V, Vohl, M-C, Völzke, H, Walker, M, Wallaschofski, H, Wild, S, Wilson, J F, Yengo, L, Bishop, D T, Borecki, I B, Chambers, J C, Cupples, L A, Dehghan, A, Deloukas, P, Fatemifar, G, Fox, C, Furey, T S, Franke, L, Han, J, Hunter, D J, Karjalainen, J, Karpe, F, Kaplan, R C, Kooner, J S, McCarthy, M I, Murabito, J M, Morris, A P, Bishop, J A N, North, K E, Ohlsson, C, Ong, K K, Prokopenko, I, Richards, J B, Schadt, E E, Spector, T D, Widén, E, Willer, C J, Yang, J, Ingelsson, E, Mohlke, K L, Hirschhorn, J N, Pospisilik, J A, Zillikens, M C, Lindgren, C, Kilpelaïnen, T O & Loos, R J F 2016, ' New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ', Nature Communications, vol. 7, 10495 . https://doi.org/10.1038/ncomms10495, Lu, Y, Day, F R, Gustafsson, S, Buchkovich, M L, Na, J, Bataille, V, Cousminer, D L, Dastani, Z, Drong, A W, Esko, T, Evans, D M, Falchi, M, Feitosa, M F, Ferreira, T, Hedman, Å K, Haring, R, Hysi, P G, Iles, M M, Justice, A E, Kanoni, S, Lagou, V, Li, R, Li, X, Locke, A, Lu, C, Mägi, R, Perry, J R B, Pers, T H, Qi, Q, Sanna, M, Schmidt, E M, Scott, W R, Shungin, D, Teumer, A, Vinkhuyzen, A A E, Walker, R W, Westra, H-J, Zhang, M, Zhang, W, Zhao, J H, Zhu, Z, Afzal, U, Ahluwalia, T S, Bakker, S J L, Bellis, C, Bonnefond, A, Borodulin, K, Buchman, A S, Cederholm, T, Choh, A C, Choi, H J, Curran, J E, de Groot, L C P G M, De Jager, P L, Dhonukshe-Rutten, R A M, Enneman, A W, Eury, E, Evans, D S, Forsen, T, Friedrich, N, Fumeron, F, Garcia, M E, Gärtner, S, Han, B-G, Havulinna, A S, Hayward, C, Hernandez, D, Hillege, H, Ittermann, T, Kent, J W, Kolcic, I, Laatikainen, T, Lahti, J, Mateo Leach, I, Lee, C G, Lee, J-Y, Liu, T, Liu, Y, Lobbens, S, Loh, M, Lyytikäinen, L-P, Medina-Gomez, C, Michaëlsson, K, Nalls, M A, Nielson, C M, Oozageer, L, Pascoe, L, Paternoster, L, Polašek, O, Ripatti, S, Sarzynski, M A, Shin, C S, Narančić, N S, Spira, D, Srikanth, P, Steinhagen-Thiessen, E, Sung, Y J, Swart, K M A, Taittonen, L, Tanaka, T, Tikkanen, E, van der Velde, N, van Schoor, N M, Verweij, N, Wright, A F, Yu, L, Zmuda, J M, Eklund, N, Forrester, T, Grarup, N, Jackson, A U, Kristiansson, K, Kuulasmaa, T, Kuusisto, J, Lichtner, P, Luan, J, Mahajan, A, Männistö, S, Palmer, C D, Ried, J S, Scott, R A, Stancáková, A, Wagner, P J, Demirkan, A, Döring, A, Gudnason, V, Kiel, D P, Kühnel, B, Mangino, M, Mcknight, B, Menni, C, O'Connell, J R, Oostra, B A, Shuldiner, A R, Song, K, Vandenput, L, van Duijn, C M, Vollenweider, P, White, C C, Boehnke, M, Boettcher, Y, Cooper, R S, Forouhi, N G, Gieger, C, Grallert, H, Hingorani, A, Jørgensen, T, Jousilahti, P, Kivimaki, M, Kumari, M, Laakso, M, Langenberg, C, Linneberg, A, Luke, A, Mckenzie, C A, Palotie, A, Pedersen, O, Peters, A, Strauch, K, Tayo, B O, Wareham, N J, Bennett, D A, Bertram, L, Blangero, J, Blüher, M, Bouchard, C, Campbell, H, Cho, N H, Cummings, S R, Czerwinski, S A, Demuth, I, Eckardt, R, Eriksson, J G, Ferrucci, L, Franco, O H, Froguel, P, Gansevoort, R T, Hansen, T, Harris, T B, Hastie, N, Heliövaara, M, Hofman, A, Jordan, J M, Jula, A, Kähönen, M, Kajantie, E, Knekt, P B, Koskinen, S, Kovacs, P, Lehtimäki, T, Lind, L, Liu, Y, Orwoll, E S, Osmond, C, Perola, M, Pérusse, L, Raitakari, O T, Rankinen, T, Rao, D C, Rice, T K, Rivadeneira, F, Rudan, I, Salomaa, V, Sørensen, T I A, Stumvoll, M, Tönjes, A, Towne, B, Tranah, G J, Tremblay, A, Uitterlinden, A G, van der Harst, P, Vartiainen, E, Viikari, J S, Vitart, V, Vohl, M-C, Völzke, H, Walker, M, Wallaschofski, H, Wild, S, Wilson, J F, Yengo, L, Bishop, D T, Borecki, I B, Chambers, J C, Cupples, L A, Dehghan, A, Deloukas, P, Fatemifar, G, Fox, C, Furey, T S, Franke, L, Han, J, Hunter, D J, Karjalainen, J, Karpe, F, Kaplan, R C, Kooner, J S, McCarthy, M I, Murabito, J M, Morris, A P, Bishop, J A N, North, K E, Ohlsson, C, Ong, K K, Prokopenko, I, Richards, J B, Schadt, E E, Spector, T D, Widén, E, Willer, C J, Yang, J, Ingelsson, E, Mohlke, K L, Hirschhorn, J N, Pospisilik, J A, Zillikens, M C, Lindgren, C, Kilpeläinen, T O & Loos, R J F 2016, ' New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ', Nature Communications, vol. 7, 10495 . https://doi.org/10.1038/ncomms10495, Nature Communications, 7:10495. Nature Publishing Group, Nature communications, 7. Nature Publishing Group, Nature Communications, 7. Nature Publishing Group, Lu, Y, Day, F R, Gustafsson, S, Buchkovich, M L, Na, J, Bataille, V, Cousminer, D L, Dastani, Z, Drong, A W, Esko, T, Evans, D M, Falchi, M, Feitosa, M F, Ferreira, T, Hedman, Å K, Haring, R, Hysi, P G, Iles, M M, Justice, A E, Kanoni, S, Lagou, V, Li, R, Li, X, Locke, A, Lu, C, Mägi, R, Perry, J R B, Pers, T H, Qi, Q, Sanna, M, Schmidt, E M, Scott, W R, Shungin, D, Teumer, A, Vinkhuyzen, A A E, Walker, R W, Westra, H-J, Zhang, M, Zhang, W, Zhao, J H, Zhu, Z, Afzal, U, Ahluwalia, T S, Bakker, S J L, Bellis, C, Bonnefond, A, Borodulin, K, Buchman, A S, Cederholm, T, Choh, A C, Choi, H J, Curran, J E, de Groot, L C P G M, De Jager, P L, Dhonukshe-Rutten, R A M, Enneman, A W, Eury, E, Evans, D S, Forsen, T, Friedrich, N, Fumeron, F, Garcia, M E, Gärtner, S, Han, B-G, Havulinna, A S, Hayward, C, Hernandez, D, Hillege, H, Ittermann, T, Kent, J W, Kolcic, I, Laatikainen, T, Lahti, J, Mateo Leach, I, Lee, C G, Lee, J-Y, Liu, T, Liu, Y, Lobbens, S, Loh, M, Lyytikäinen, L-P, Medina-Gomez, C, Michaëlsson, K, Nalls, M A, Nielson, C M, Oozageer, L, Pascoe, L, Paternoster, L, Polašek, O, Ripatti, S, Sarzynski, M A, Shin, C S, Narančić, N S, Spira, D, Srikanth, P, Steinhagen-Thiessen, E, Sung, Y J, Swart, K M A, Taittonen, L, Tanaka, T, Tikkanen, E, van der Velde, N, van Schoor, N M, Verweij, N, Wright, A F, Yu, L, Zmuda, J M, Eklund, N, Forrester, T, Grarup, N, Jackson, A U, Kristiansson, K, Kuulasmaa, T, Kuusisto, J, Lichtner, P, Luan, J, Mahajan, A, Männistö, S, Palmer, C D, Ried, J S, Scott, R A, Stancáková, A, Wagner, P J, Demirkan, A, Döring, A, Gudnason, V, Kiel, D P, Kühnel, B, Mangino, M, Mcknight, B, Menni, C, O'Connell, J R, Oostra, B A, Shuldiner, A R, Song, K, Vandenput, L, van Duijn, C M, Vollenweider, P, White, C C, Boehnke, M, Boettcher, Y, Cooper, R S, Forouhi, N G, Gieger, C, Grallert, H, Hingorani, A, Jørgensen, T, Jousilahti, P, Kivimaki, M J, Kumari, M, Laakso, M, Langenberg, C, Linneberg, A, Luke, A, Mckenzie, C A, Palotie, A, Pedersen, O, Peters, A, Strauch, K, Tayo, B O, Wareham, N J, Bennett, D A, Bertram, L, Blangero, J, Blüher, M, Bouchard, C, Campbell, H, Cho, N H, Cummings, S R, Czerwinski, S A, Demuth, I, Eckardt, R, Eriksson, J G, Ferrucci, L, Franco, O H, Froguel, P, Gansevoort, R T, Hansen, T, Harris, T B, Hastie, N, Heliövaara, M, Hofman, A, Jordan, J M, Jula, A, Kähönen, M, Kajantie, E, Knekt, P B, Koskinen, S, Kovacs, P, Lehtimäki, T, Lind, L, Liu, Y, Orwoll, E S, Osmond, C, Perola, M, Pérusse, L, Raitakari, O T, Rankinen, T, Rao, D C, Rice, T K, Rivadeneira, F, Rudan, I, Salomaa, V, Sorensen, T, Stumvoll, M, Tönjes, A, Towne, B, Tranah, G J, Tremblay, A, Uitterlinden, A G, van der Harst, P, Vartiainen, E, Viikari, J S, Vitart, V, Vohl, M-C, Völzke, H, Walker, M, Wallaschofski, H, Wild, S, Wilson, J F, Yengo, L, Bishop, D T, Borecki, I B, Chambers, J C, Cupples, L A, Dehghan, A, Deloukas, P, Fatemifar, G, Fox, C, Furey, T S, Franke, L, Han, J, Hunter, D J, Karjalainen, J, Karpe, F, Kaplan, R C, Kooner, J S, McCarthy, M I, Murabito, J M, Morris, A P, Bishop, J A N, North, K E, Ohlsson, C, Ong, K K, Prokopenko, I, Richards, J B, Schadt, E E, Spector, T D, Widén, E, Willer, C J, Yang, J, Ingelsson, E, Mohlke, K L, Hirschhorn, J N, Pospisilik, J A, Zillikens, M C, Lindgren, C, Kilpeläinen, T O & Loos, R J F 2016, ' New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ', Nature Communications, vol. 7, 10495 . https://doi.org/10.1038/ncomms10495, Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016), Lu, Y, Day, F R, Gustafsson, S, Buchkovich, M L, Na, J, Bataille, V, Cousminer, D L, Dastani, Z, Drong, A W, Esko, T, Evans, D M, Falchi, M, Feitosa, M F, Ferreira, T, Hedman, Å K, Haring, R, Hysi, P G, Iles, M M, Justice, A E, Kanoni, S, Lagou, V, Li, R, Li, X, Locke, A, Lu, C, Mägi, R, Perry, J R B, Pers, T H, Qi, Q, Sanna, M, Schmidt, E M, Scott, W R, Shungin, D, Teumer, A, Vinkhuyzen, A A E, Walker, R W, Westra, H-J, Zhang, M, Zhang, W, Zhao, J H, Zhu, Z, Afzal, U, Ahluwalia, T S, Bakker, S J L, Bellis, C, Bonnefond, A, Borodulin, K, Buchman, A S, Cederholm, T, Choh, A C, Choi, H J, Curran, J E, de Groot, L C P G M, De Jager, P L, Dhonukshe-Rutten, R A M, Enneman, A W, Eury, E, Evans, D S, Forsen, T, Friedrich, N, Fumeron, F, Garcia, M E, Gärtner, S, Han, B-G, Havulinna, A S, Hayward, C, Hernandez, D, Hillege, H, Ittermann, T, Kent, J W, Kolcic, I, Laatikainen, T, Lahti, J, Mateo Leach, I, Lee, C G, Lee, J-Y, Liu, T, Liu, Y, Lobbens, S, Loh, M, Lyytikäinen, L-P, Medina-Gomez, C, Michaëlsson, K, Nalls, M A, Nielson, C M, Oozageer, L, Pascoe, L, Paternoster, L, Polašek, O, Ripatti, S, Sarzynski, M A, Shin, C S, Narančić, N S, Spira, D, Srikanth, P, Steinhagen-Thiessen, E, Sung, Y J, Swart, K M A, Taittonen, L, Tanaka, T, Tikkanen, E, van der Velde, N, van Schoor, N M, Verweij, N, Wright, A F, Yu, L, Zmuda, J M, Eklund, N, Forrester, T, Grarup, N, Jackson, A U, Kristiansson, K, Kuulasmaa, T, Kuusisto, J, Lichtner, P, Luan, J, Mahajan, A, Männistö, S, Palmer, C D, Ried, J S, Scott, R A, Stancáková, A, Wagner, P J, Demirkan, A, Döring, A, Gudnason, V, Kiel, D P, Kühnel, B, Mangino, M, Mcknight, B, Menni, C, O'Connell, J R, Oostra, B A, Shuldiner, A R, Song, K, Vandenput, L, van Duijn, C M, Vollenweider, P, White, C C, Boehnke, M, Boettcher, Y, Cooper, R S, Forouhi, N G, Gieger, C, Grallert, H, Hingorani, A, Jørgensen, T, Jousilahti, P, Kivimaki, M, Kumari, M, Laakso, M, Langenberg, C, Linneberg, A, Luke, A, Mckenzie, C A, Palotie, A, Pedersen, O, Peters, A, Strauch, K, Tayo, B O, Wareham, N J, Bennett, D A, Bertram, L, Blangero, J, Blüher, M, Bouchard, C, Campbell, H, Cho, N H, Cummings, S R, Czerwinski, S A, Demuth, I, Eckardt, R, Eriksson, J G, Ferrucci, L, Franco, O H, Froguel, P, Gansevoort, R T, Hansen, T, Harris, T B, Hastie, N, Heliövaara, M, Hofman, A, Jordan, J M, Jula, A, Kähönen, M, Kajantie, E, Knekt, P B, Koskinen, S, Kovacs, P, Lehtimäki, T, Lind, L, Liu, Y, Orwoll, E S, Osmond, C, Perola, M, Pérusse, L, Raitakari, O T, Rankinen, T, Rao, D C, Rice, T K, Rivadeneira, F, Rudan, I, Salomaa, V, Sørensen, T I A, Stumvoll, M, Tönjes, A, Towne, B, Tranah, G J, Tremblay, A, Uitterlinden, A G, van der Harst, P, Vartiainen, E, Viikari, J S, Vitart, V, Vohl, M-C, Völzke, H, Walker, M, Wallaschofski, H, Wild, S, Wilson, J F, Yengo, L, Bishop, D T, Borecki, I B, Chambers, J C, Cupples, L A, Dehghan, A, Deloukas, P, Fatemifar, G, Fox, C, Furey, T S, Franke, L, Han, J, Hunter, D J, Karjalainen, J, Karpe, F, Kaplan, R C, Kooner, J S, McCarthy, M I, Murabito, J M, Morris, A P, Bishop, J A N, North, K E, Ohlsson, C, Ong, K K, Prokopenko, I, Richards, J B, Schadt, E E, Spector, T D, Widén, E, Willer, C J, Yang, J, Ingelsson, E, Mohlke, K L, Hirschhorn, J N, Pospisilik, J A, Zillikens, M C, Lindgren, C, Kilpeläinen, T O & Loos, R J F 2016, ' New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ', Nature Communications, vol. 7, pp. 10495 . https://doi.org/10.1038/ncomms10495, Nature Communications, 7, Nature Communications, vol. 7, pp. 10495, Lu, Y, Day, F R, Gustafsson, S, Buchkovich, M L, Na, J, Bataille, V, Cousminer, D L, Dastani, Z, Drong, A W, Esko, T, Evans, D M, Falchi, M, Feitosa, M F, Ferreira, T, Hedman, A K, Haring, R, Hysi, P G, Iles, M M, Justice, A E, Kanoni, S, Lagou, V, Li, R, Li, X, Locke, A, Lu, C, Magi, R, Perry, J R B, Pers, T H, Qi, Q, Sanna, M, Schmidt, E M, Scott, W R, Shungin, D, Teumer, A, Vinkhuyzen, A A E, Walker, R W, Westra, H-J, Zhang, M, Zhang, W, Zhao, J H, Zhu, Z, Afzal, U, Ahluwalia, T S, Bakker, S J L, Bellis, C, Bonnefond, A, Borodulin, K, Buchman, A S, Cederholm, T, Choh, A C, Choi, H J, Curran, J E, de Groot, L C P G M, De Jager, P L, Dhonukshe-Rutten, R A M, Enneman, A W, Eury, E, Evans, D S, Forsen, T, Friedrich, N, Fumeron, F, Garcia, M E, Gartner, S, Han, B-G, Havulinna, A S, Hayward, C, Hernandez, D, Hillege, H, Ittermann, T, Kent, J W, Kolcic, I, Laatikainen, T, Lahti, J, Leach, I M, Lee, C G, Lee, J-Y, Liu, T, Liu, Y, Lobbens, S, Loh, M, Lyytikainen, L-P, Medina-Gomez, C, Michaelsson, K, Nalls, M A, Nielson, C M, Oozageer, L, Pascoe, L, Paternoster, L, Polasek, O, Ripatti, S, Sarzynski, M A, Shin, C S, Narancic, N S, Spira, D, Srikanth, P, Steinhagen-Thiessen, E, Sung, Y J, Swart, K M A, Taittonen, L, Tanaka, T, Tikkanen, E, van der Velde, N, van Schoor, N M, Verweij, N, Wright, A F, Yu, L, Zmuda, J M, Eklund, N, Forrester, T, Grarup, N, Jackson, A U, Kristiansson, K, Kuulasmaa, T, Kuusisto, J, Lichtner, P, Luan, J, Mahajan, A, Mannisto, S, Palmer, C D, Ried, J S, Scott, R A, Stancakova, A, Wagner, P J, Demirkan, A, Doring, A, Gudnason, V, Kiel, D P, Kuhnel, B, Mangino, M, Mcknight, B, Menni, C, O'Connell, J R, Oostra, B A, Shuldiner, A R, Song, K, Vandenput, L, van Duijn, C M, Vollenweider, P, White, C C, Boehnke, M, Boettcher, Y, Cooper, R S, Forouhi, N G, Gieger, C, Grallert, H, Hingorani, A, Jorgensen, T, Jousilahti, P, Kivimaki, M, Kumari, M, Laakso, M, Langenberg, C, Linneberg, A, Luke, A, Mckenzie, C A, Palotie, A, Pedersen, O, Peters, A, Strauch, K, Tayo, B O, Wareham, N J, Bennett, D A, Bertram, L, Blangero, J, Bluher, M, Bouchard, C, Campbell, H, Cho, N H, Cummings, S R, Czerwinski, S A, Demuth, I, Eckardt, R, Eriksson, J G, Ferrucci, L, Franco, O H, Froguel, P, Gansevoort, R T, Hansen, T, Harris, T B, Hastie, N, Heliovaara, M, Hofman, A, Jordan, J M, Jula, A, Kahonen, M, Kajantie, E, Knekt, P B, Koskinen, S, Kovacs, P, Lehtimaki, T, Lind, L, Liu, Y, Orwoll, E S, Osmond, C, Perola, M, Perusse, L, Raitakari, O T, Rankinen, T, Rao, D C, Rice, T K, Rivadeneira, F, Rudan, I, Salomaa, V, Sorensen, T I A, Stumvoll, M, Tonjes, A, Towne, B, Tranah, G J, Tremblay, A, Uitterlinden, A G, van der Harst, P, Vartiainen, E, Viikari, J S, Vitart, V, Vohl, M-C, Volzke, H, Walker, M, Wallaschofski, H, Wild, S, Wilson, J F, Yengo, L, Bishop, D T, Borecki, I B, Chambers, J C, Cupples, L A, Dehghan, A, Deloukas, P, Fatemifar, G, Fox, C, Furey, T S, Franke, L, Han, J, Hunter, D J, Karjalainen, J, Karpe, F, Kaplan, R C, Kooner, J S, McCarthy, M I, Murabito, J M, Morris, A P, Bishop, J A N, North, K E, Ohlsson, C, Ong, K K, Prokopenko, I, Richards, J B, Schadt, E E, Spector, T D, Widen, E, Willer, C J, Yang, J, Ingelsson, E, Mohlke, K L, Hirschhorn, J N, Pospisilik, J A, Zillikens, M C, Lindgren, C, Kilpelainen, T O & Loos, R J F 2016, ' y New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ', Nature Communications, vol. 7, 10495 . https://doi.org/10.1038/ncomms10495, Nature Communications 7 (2016)
- Publication Year :
- 2015
-
Abstract
- To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic disease risk, we conducted a genome-wide association meta-analysis of body fat percentage (BF%) in up to 100,716 individuals. Twelve loci reached genome-wide significance (P<br />A genome-wide association meta-analysis study here shows novel genetic loci to be associated to body fat percentage, and describes cross-phenotype association that further demonstrate a close relationship between adiposity and cardiovascular disease risk.
- Subjects :
- 0301 basic medicine
Medicin och hälsovetenskap
Drosophila melanogaster/genetics
Nutrition and Disease
General Physics and Astronomy
Genome-wide association study
Medical and Health Sciences
Body fat percentage
Voeding en Ziekte
CUTANEOUS NEVI
Mass index
Human Nutrition & Health
Adiposity
INSULIN-RESISTANCE
Multidisciplinary
body fat
cardiometabolic traits
genome-wide association study
meta-analysis
biology
Disease genetics
Leptin
Humane Voeding & Gezondheid
COMMON VARIANTS
Public Health, Global Health, Social Medicine and Epidemiology
3. Good health
Biological sciences
Cardiovascular diseases
Drosophila melanogaster
Gene Knockdown Techniques
ENERGY-BALANCE
Medical Genetics
medicine.medical_specialty
SUSCEPTIBILITY LOCI
Heart Diseases
515 Psychology
Science
Quantitative Trait Loci
PROVIDES INSIGHTS
Quantitative trait locus
General Biochemistry, Genetics and Molecular Biology
Article
GENETIC ARCHITECTURE
03 medical and health sciences
MASS INDEX
Insulin resistance
Internal medicine
MD Multidisciplinary
Genetics
medicine
Life Science
Animals
Humans
Genetic Predisposition to Disease
GENOME-WIDE ASSOCIATION
Medicinsk genetik
VLAG
Global Nutrition
Wereldvoeding
Gene Expression Regulation/physiology
C-reactive protein
Metabolic diseases
General Chemistry
ta3121
medicine.disease
Onderwijsinstituut
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
Adiposity/genetics
Drosophila melanogaster/metabolism
Genome-Wide Association Study
Heart Diseases/genetics
Quantitative Trait Loci/genetics
030104 developmental biology
Endocrinology
Gene Expression Regulation
3121 General medicine, internal medicine and other clinical medicine
biology.protein
Lean body mass
IDENTIFIES COMMON
Subjects
Details
- ISSN :
- 20411723
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Nature communications
- Accession number :
- edsair.doi.dedup.....c7ecce342c6172985e54851035d00401