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Correspondence on: ‘Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort’ by Poulettyet al

Authors :
Iolanda Jordan
Iván Cano
Mariona F De Sevilla
Claudia Fortuny
Cristina Esteva
Silvia Ricart
Juan Manuel Mosquera
Manuel Monsonís
María Ríos-Barnés
Cristian Launes
Antoni Noguera-Julian
Victoria Fumadó
Juan José García García
Carmen Muñoz-Almagro
Joan Sánchez de Toledo
Judith Sánchez Manubens
Rosa Pino
Ana Carolina Izurieta
Laura Monfort
Jordi Anton
Laura Lecina
Source :
Annals of the Rheumatic Diseases
Publication Year :
2020
Publisher :
BMJ, 2020.

Abstract

We read with interest the article by Pouletty et al ,1 in which the authors describe a multicentre compilation of patients with Kawasaki disease (KD) in France, associated with the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Other colleagues in Europe and USA have recently reported similar experiences.2–5 We report a prospective case series of paediatric patients that fulfilled clinical diagnostic criteria of KD during the SARS-CoV-2 pandemic in a paediatric referral centre in Barcelona, Spain. KD was defined according to the 2017 criteria of the American Heart Association.6 Assessment of SARS-CoV-2 infection was made by means of quantitative real-time PCR assay (GeneFinder COVID-19 Plus, Elitech; Puteaux, France) in nasopharyngeal samples; stools were tested in patients with diarrhoea. SARS-CoV-2 IgG qualitative determination (SARS-CoV-2 IgG chemiluminescent microparticle immunoassay; Abbot, Chicago, Illinois) was performed during admission. Statistical analyses were performed using SPSS V.25 (IBM). Informed consent was obtained from parents or legal guardians, as was informed assent in patients aged >12 years. From March 23 to May 14, twelve previously healthy patients with KD were admitted to our institution (table 1). The yearly number of patients with KD diagnosed in our centre is around 10–12. Prior to diagnosis, several patients reported gastrointestinal symptoms (10/12, 83.3%; vomiting, diarrhoea and abdominal pain) and neurological symptoms (5/12, 41.6%; irritability, headache, decreased consciousness and febrile seizures). Only patient 10 was referred with respiratory symptoms …

Details

ISSN :
14682060 and 00034967
Volume :
81
Database :
OpenAIRE
Journal :
Annals of the Rheumatic Diseases
Accession number :
edsair.doi.dedup.....c85d01c0372336c767ec8d7ddff2c997
Full Text :
https://doi.org/10.1136/annrheumdis-2020-218538