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Mapping the eight-item Parkinson's Disease Questionnaire (PDQ-8) to the EQ-5D utility index
- Source :
- Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 17(9)
- Publication Year :
- 2008
-
Abstract
- To develop a function for mapping the eight-item Parkinson's Disease Questionnaire (PDQ-8) to the EuroQol Group's EQ-5D utility index.Data from two surveys of 324 patients with Parkinson's disease was divided into two groups. One was used to estimate the mapping functions by regression methods and the other was used to validate the mapping functions.A regression model with a non-linear trend explained 55% of the variation in EQ-5D utility values and had a mean absolute deviation (MAD) of 0.083. A regression model assuming a linear trend explained 52% of the variation and had an MAD of 0.085. In the validation sample, predicted values based on the aforementioned models respectively explained 42 and 44% of the variation in the observed EQ-5D utility values and both had MADs of about 0.1. The confidence intervals of the mean difference between these predicted values and the observed values totally fell within the pre-defined equivalence margin of 0.03 points. These predicted values were also similar to the observed EQ-5D utility values in terms of their association with clinical variables.At the group level, but not at the individual level, the mapping functions can accurately map the PDQ-8 outcomes to the EQ-5D utility index.
- Subjects :
- Adult
Male
medicine.medical_specialty
Index (economics)
Parkinson's disease
Health utility
Health Status
Quality of life
EQ-5D
Surveys and Questionnaires
Statistics
Medicine
Humans
Quality of Life Research
Aged
Aged, 80 and over
Singapore
business.industry
Public Health, Environmental and Occupational Health
Parkinson Disease
Middle Aged
medicine.disease
humanities
Physical therapy
Quality of Life
Female
business
human activities
Subjects
Details
- ISSN :
- 09629343
- Volume :
- 17
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
- Accession number :
- edsair.doi.dedup.....c86019022e4cb6fd78d64c9b925b216e