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Clinical usefulness of instantaneous wave-free ratio for the evaluation of coronary artery lesion with prior myocardial infarction: A multi-center study
- Source :
- International Journal of Cardiology. Heart & Vasculature, International Journal of Cardiology: Heart & Vasculature, Vol 26, Iss, Pp-(2020)
- Publication Year :
- 2019
-
Abstract
- Background: Fractional flow reserve (FFR) is useful for assessing the functional significance of coronary artery stenosis, even in lesions with prior myocardial infarction (pMI). Instantaneous wave-free ratio (iFR) is a vasodilator-free alternative for the physiological assessment of coronary artery stenosis. In addition, iFR shows good diagnostic agreement with FFR and an iFR-guided revascularization strategy was non-inferior to an FFR-guided revascularization strategy. However, the clinical usefulness of iFR for the evaluation of a coronary artery lesions with pMI has not been evaluated. Methods and Results: A total of 200 lesions from 200 patients (44 pMI territories lesions and 156 non-pMI coronary artery lesions) were analyzed retrospectively. Major adverse cardiac events (MACE) were defined as cardiovascular death, non-fatal MI, unstable angina pectoris, fatal arrhythmia and heart failure during 12 months follow-up after the physiological assessment of coronary artery stenosis. iFR was closely correlated with FFR in pMI and non-pMI lesions (r = 0.81 and 0.72; P
- Subjects :
- Instantaneous wave-free ratio
FFR, fractional flow reserve
medicine.medical_specialty
lcsh:Diseases of the circulatory (Cardiovascular) system
medicine.medical_treatment
CAD, coronary artery disease
IMR, index of micro-circulatory resistance
MACE, major adverse cardiac event
Fractional flow reserve
030204 cardiovascular system & hematology
Revascularization
Coronary artery disease
HF, heart failure
03 medical and health sciences
0302 clinical medicine
Internal medicine
DM, diabetes mellitus
UAP, unstable angina pectoris
LVEF, left ventricular ejection fraction
medicine
030212 general & internal medicine
Myocardial infarction
Original Paper
PCI, percutaneous coronary intervention
business.industry
Unstable angina
CFR, coronary flow reserve
medicine.disease
Prognosis
Prior myocardial infarction
AMI, acute myocardial infarction
lcsh:RC666-701
Heart failure
Cardiology
iFR, instantaneous wave-free ratio
pMI, prior myocardial infarction
Cardiology and Cardiovascular Medicine
business
MRI, magnetic resonance imaging
Mace
Subjects
Details
- ISSN :
- 23529067
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- International journal of cardiology. Heartvasculature
- Accession number :
- edsair.doi.dedup.....c870ac38bdc184401367c71b6d9ca051