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Nitrogen plasma skin regeneration for the treatment of mild‐to‐moderate periorbital wrinkles: A prospective, randomized, controlled evaluator‐blinded trial

Authors :
Montree Udompataikul
Piyakan Limtanyakul
Thep Chalermchai
Suwirakorn Ophaswongse
Naphatsanan Theppornpitak
Source :
Journal of Cosmetic Dermatology. 18:163-168
Publication Year :
2018
Publisher :
Wiley, 2018.

Abstract

BACKGROUND Nitrogen plasma skin regeneration is a novel device that produces heat to the skin, resulting in the production of new collagen. Because of lower energy with safer skin damage and lesser adverse effects who have high Fitzpatrick's skin type especially Thais, this technique is very interesting for clinical application for skin esthetic treatment. However, this treatment has yet been empirically studied as the treatment for mild-to-moderate periorbital wrinkles. OBJECTIVES This study aimed to evaluate clinical efficacy of nitrogen plasma for the treatment of mild-to-moderate periorbital wrinkles. METHODS Eighteen volunteers were enrolled. Each volunteer was randomized to receive nitrogen plasma treatment on one side of periorbital wrinkles with three sessions at a three-week interval and compared with contralateral side without treatment. Photographic examination, skin wrinkle (SEw) score, melanin index, patients' satisfaction score, side effect, and pain score were reported. RESULTS At over fourteen weeks, all volunteers completed the study. Treatment with nitrogen plasma group had significantly better improvement for periorbital wrinkles score by Lemperle scale, skin wrinkle (SEw) score by Visioscan® VC 98, and the melanin index by Mexameter® than the control groups (P = 0.004, P

Details

ISSN :
14732165 and 14732130
Volume :
18
Database :
OpenAIRE
Journal :
Journal of Cosmetic Dermatology
Accession number :
edsair.doi.dedup.....c889638b4f9ab444add36816713c425c