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Profile of GenMark’s ePlex® blood culture identification fungal pathogen panel
- Source :
- Expert Review of Molecular Diagnostics, Expert Review of Molecular Diagnostics, Expert Reviews (formerly Future Drugs), 2017, pp.1-14. ⟨10.1080/14737159.2018.1420476⟩
- Publication Year :
- 2017
- Publisher :
- Informa UK Limited, 2017.
-
Abstract
- International audience; Fungemia presents high morbi-mortality and thus rapid microbiological diagnosis may contribute to appropriate patient management. In the last decade, kits based on molecular technologies have become available and health care institutes are increasingly facing critical investment choices. Although all these tools aim to achieve rapid fungal detection and species identification, they display different inherent characteristics. Areas covered: Considering technologies allowing detection and identification of fungal species in a sepsis context, the market proposes either tests on positive blood culture or tests on patient's whole blood. In this review, the authors describe and compare the ePlex® Blood Culture Identification Fungal Pathogen (BCID-FP) test, a fully automated one-step single-use cartridge assay that has been designed to detect identify frequent or rare but emerging, fungal species, from positive blood culture. A comparison with the competing kits is provided. Expert commentaries: The ePlex BCID-FP test provides a diversified and rather relevant panel. Its easy-to-use cartridges allow flexible use around the clock. Nevertheless, prospective clinical studies assessing the time-to-result benefit on antifungal stewardship and on hospital length of stay are not available yet. New tools aim to benefit clinicians and patients, but they should be accompanied by supervision of result interpretation and adaptation of antifungal stewardship.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
antifungal stewardship
diagnosis
030106 microbiology
Context (language use)
invasive fungal infection
blood culture
Pathology and Forensic Medicine
Sepsis
03 medical and health sciences
Health care
Genetics
Humans
Medicine
Blood culture
Intensive care medicine
Molecular Biology
[SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology
Fungemia
medicine.diagnostic_test
business.industry
candidemia
Fungi
Reproducibility of Results
molecular diagnostic
Fungal pathogen
medicine.disease
3. Good health
PCR
Molecular Diagnostic Techniques
Mycoses
Molecular Medicine
Identification (biology)
Reagent Kits, Diagnostic
Stewardship
business
Subjects
Details
- ISSN :
- 17448352 and 14737159
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- Expert Review of Molecular Diagnostics
- Accession number :
- edsair.doi.dedup.....c8a546359c39a84333bba45b3342ecf9
- Full Text :
- https://doi.org/10.1080/14737159.2018.1420476