Sub-lethal ionizing radiation alters Foxp3 expression in CD4+ T regulatory (Treg) cells in vitro and in vivo

Meeting abstracts The use of sub-lethal radiation has been shown to alter cell phenotype and gene expression. T regulatory (Treg) cells are phenotypically defined as being CD4+CD25+ Foxp3+ T cells and are known to suppress the function of CD8+ cytotoxic T lymphocytes (CTLs). Inhibiting the