18F-FDOPA PET/CT of Paraganglioma in the Spermatic Cord

Authors :: Goujon, Anna
Pop, Gabriel
Hissier, Julien
Moreau, Benjamin
Palard-Novello, Xavier
CHU Pontchaillou [Rennes]
Centre Eugène Marquis (CRLCC)
Laboratoire Traitement du Signal et de l'Image (LTSI)
Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Source :: Clinical Nuclear Medicine, Clinical Nuclear Medicine, 2023, 48 (5), pp.E232-E234. ⟨10.1097/RLU.0000000000004616⟩
Publication Year :: 2023
Publisher :: Ovid Technologies (Wolters Kluwer Health), 2023.
Abstract: International audience; A 53-year-old man with chronic kidney failure was referred to perform an F-18-FDOPA PET/CT to characterize a mass located on the right spermatic cord. Previously, the pathological analysis of CT-guided biopsies suggested paraganglioma or metastatic lesion of pheochromocytoma. Serum normetanephrine and serum metanephrine values were respectively 2- and 1.5-fold greater than the normal upper limit, which could be explained by the chronic kidney failure. PET/CT images revealed intense F-18-FDOPA uptake of the mass without any other pathological findings, suggesting the diagnosis of paraganglioma. Pathological examination of surgical specimen confirmed the diagnosis of paraganglioma of the spermatic cord, which is exceptional.