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Experience With the Radioimmunoassay for Parathyroid Hormone in the Diagnosis of Primary Hyperparathyroidism
- Source :
- Journal of Urology. 119:175-179
- Publication Year :
- 1978
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 1978.
-
Abstract
- Our results with radioimmunoassay studies for parathyroid hormone performed during the last 6 years are compared retrospectively to results of the laboratory tests customarily secured when hyperparathyroidism is suspected. The results obtained in patients with known primary hyperparathyroidism and in patients with unconfirmed but presumptive hyperparathyroidism are compared to the results obtained from a group of normal controls. Despite the fact that certain discrepant results were noted in the earlier assay techniques the over-all results and, in particular, those of more recent years have been highly sensitive and reproducible corroboratives of the existence of primary hyperparathyroidism. About two-thirds of the patients with primary hyperparathyroidism will present to the urologist. All patients with calcium-containing stones should have at least 3 determinations of the serum calcium in screening for primary hyperparathyroidism. The radioimmunoassay for parathyroid hormone provides the most reliable confirmation. The patient with calculous disease, elevation of the immunoreactive parathyroid hormone level and hypercalcemia is virtually certain to have primary hyperparathyroidism.
- Subjects :
- Pathology
medicine.medical_specialty
endocrine system diseases
Urology
Guinea Pigs
Radioimmunoassay
Parathyroid hormone
medicine
Animals
Humans
In patient
Antigens
Clinical Trials as Topic
Hyperparathyroidism
business.industry
Phosphorus
medicine.disease
Highly sensitive
Parathyroid Hormone
Hypercalcemia
Calcium
Urinary Calculi
business
Primary hyperparathyroidism
Subjects
Details
- ISSN :
- 15273792 and 00225347
- Volume :
- 119
- Database :
- OpenAIRE
- Journal :
- Journal of Urology
- Accession number :
- edsair.doi.dedup.....c951307c51892a83a3de947799598662