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Brain tumour risk in relation to mobile telephone use: results of the INTERPHONE international case-control study
- Source :
- Johansen, C 2010, ' Brain tumour risk in relation to mobile telephone use : results of the INTERPHONE international case-control study ', International Journal of Epidemiology, vol. 39, no. 3, pp. 675-94 . https://doi.org/10.1093/ije/dyq079, International Journal of Epidemiology, International Journal of Epidemiology, Oxford University Press (OUP), 2010, 39 (3), pp.675. ⟨10.1093/ije/DYQ079⟩
- Publication Year :
- 2010
- Publisher :
- Oxford University Press (OUP), 2010.
-
Abstract
- International audience; Background: The rapid increase in mobile telephone use has generated concern about possible health risks related to radiofrequency electromagnetic fields from this technology. Methods: An interview-based case-control study with 2708 glioma and 2409 meningioma cases and matched controls was conducted in 13 countries using a common protocol. Results: A reduced odds ratio (OR) related to ever having been a regular mobile phone user was seen for glioma (OR 0.81, 95% confidence interval (CI): 0.70, 0.94) and meningioma (OR 0.79; 95% CI 0.68, 0.91), possibly reflecting participation bias or other methodological limitations. No elevated OR was observed 10 or more years after first phone use (glioma: OR 0.98, 95% CI 0.76, 1.26; meningioma: OR 0.83, 95% CI 0.61, 1.14). Odds ratios were below 1.0 for all deciles of lifetime number of phone calls and nine deciles of cumulative call time. In the tenth decile of recalled cumulative call time, 1640 hours or longer, the odds ratio was 1.40 (95% CI 1.03, 1.89) for glioma, and 1.15 (95% CI 0.81, 1.62) for meningioma; but there are implausible values of reported use in this group. Odds ratios for glioma tended to be greater in the temporal lobe than in other lobes of the brain, but the confidence intervals around the lobe-specific estimates were wide. Odds ratios for glioma tended to be greater in subjects who reported usual phone use on the same side of the head as their tumour than on the opposite side. Conclusions: Overall, no increase in risk of glioma or meningioma was observed with use of mobile phones. There were suggestions of an increased risk of glioma at the highest exposure levels, but biases and error prevent a causal interpretation. The possible effects of long-term heavy use of mobile phones require further investigation.
- Subjects :
- Adult
Male
Oncology
medicine.medical_specialty
Pathology
Relation (database)
Epidemiology
Mobile telephone
Meningioma
03 medical and health sciences
Electromagnetic Fields
0302 clinical medicine
Glioma
Internal medicine
Odds Ratio
medicine
Humans
030212 general & internal medicine
neoplasms
mobile phones
Brain Neoplasms
business.industry
Brain tumours
Case-control study
General Medicine
Middle Aged
medicine.disease
3. Good health
nervous system diseases
Increased risk
Case-Control Studies
030220 oncology & carcinogenesis
Cellular Phone
Medicine
Female
radiofrequency fields
business
Cell Phone
Subjects
Details
- Language :
- English
- ISSN :
- 03005771 and 14643685
- Database :
- OpenAIRE
- Journal :
- Johansen, C 2010, ' Brain tumour risk in relation to mobile telephone use : results of the INTERPHONE international case-control study ', International Journal of Epidemiology, vol. 39, no. 3, pp. 675-94 . https://doi.org/10.1093/ije/dyq079, International Journal of Epidemiology, International Journal of Epidemiology, Oxford University Press (OUP), 2010, 39 (3), pp.675. ⟨10.1093/ije/DYQ079⟩
- Accession number :
- edsair.doi.dedup.....c9c4c0dc60dfc91b31cdf176a2e2614f