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Fatty liver index correlates with non-alcoholic fatty liver disease, but not with newly diagnosed coronary artery atherosclerotic disease in Chinese patients
- Source :
- BMC Gastroenterology
- Publication Year :
- 2012
-
Abstract
- Background Fatty liver index (FLI) was recently established to predict non-alcoholic fatty liver disease (NAFLD) in general population, which is known to be associated with coronary artery atherosclerotic disease (CAD). This study aims to investigate whether FLI correlates with NAFLD and with newly diagnosed CAD in a special Chinese population who underwent coronary angiography. Methods Patients with CAD (n = 231) and without CAD (n = 482) as confirmed by coronary angiography were included. Among them, 574 patients underwent B-ultrosonography were divided into NAFLD group (n = 209) and non-NAFLD group (n = 365). Correlation between FLI and NAFLD was analyzed using pearson’s correlation. The associations between FLI and NAFLD as well as CAD were assessed using logistic regression. The predictive accuracy of FLI for NAFLD was evaluated using receiver operating characteristics (ROC) curve analysis. Results FLI was significantly higher in NAFLD group (37.10 ± 1.95) than in non-NAFLD group (17.70 ± 1.04), P 0.05). Conclusions FLI showed good correlation with NAFLD in patients who underwent coronary angiography, but not with newly diagnosed CAD. This might be underestimated because some patients in non-CAD group may have other underlying cardiovascular diseases.
- Subjects :
- Male
medicine.medical_specialty
China
Coronary angiography
Population
Disease
Coronary Artery Disease
Body Mass Index
Coronary artery disease
Non-alcoholic Fatty Liver Disease
Internal medicine
medicine
Confidence Intervals
Odds Ratio
Humans
Gamma-glutamyltransferase
education
Triglycerides
Ultrasonography
education.field_of_study
biology
Fatty liver index
business.industry
Fatty liver
fungi
Gastroenterology
nutritional and metabolic diseases
General Medicine
Odds ratio
gamma-Glutamyltransferase
Hepatology
medicine.disease
Coronary artery atherosclerotic disease
digestive system diseases
Fatty Liver
Radiography
Logistic Models
ROC Curve
Area Under Curve
Cardiology
biology.protein
Female
Waist Circumference
business
Body mass index
Algorithms
Biomarkers
Research Article
Subjects
Details
- ISSN :
- 1471230X
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- BMC gastroenterology
- Accession number :
- edsair.doi.dedup.....ca5df51af2306338494d34be01770ec3