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Prevalence and antimicrobial susceptibility pattern of uropathogenic organisms among diabetic patients attending State Specialist Hospital, Maiduguri Nigeria

Prevalence and antimicrobial susceptibility pattern of uropathogenic organisms among diabetic patients attending State Specialist Hospital, Maiduguri Nigeria

Authors :
Wathanafa Madu
Musa Joseph Bamaiyi
Monilade Tawa Akinola
Muhammed Talle
Hamidu M. Ibrahim
Idris Nasir Abdullahi
Muhammad Mustapha
Marycelin Mandu Baba
Bamidele Soji Oderinde
Source :
Sokoto Journal of Medical Laboratory Science; Vol. 7 No. 3 (2022); 102-113
Publication Year :
2022
Publisher :
African Journals Online (AJOL), 2022.

Abstract

Urinary tract infection (UTI) is the colonization of the urinary tract by pathogenic microorganisms. There is paucity of data on the development of multidrug resistant uropathogenic strains associated with Diabetes Mellitus (DM). In this cross-sectional study we investigated a total of three hundred and thirty (330) known diabetes mellitus (DM) patients, comprising of 06 (1.8%) Type I DM, 296 (89.7%) Type II DM and 28 (8.5%) Gestational Diabetes patients aged 21 to 80 years. The subjects consisted of 150 males (45.5%) and 180 (54.5%) females. Urine culture was carried out on CLED, MacConkey and blood agar and Kirby Bauer disc diffusion for antimicrobial susceptibility testing was carried out to determine the susceptibility of the isolated organisms to commonly used antimicrobials in the study area. The study revealed that one hundred and twenty-two (37%) yielded significant bacterial growth. The percentage distribution of the organisms isolated are as follows; Staphylococci (10.6%), Klebsiella spp. (13.2%), Coliforms spp. (13.9%), Staphylococcus aureus (24.6%) and Escherichia coli has the highest occurrence of (37.7%). Gram negative bacteria isolated were highly susceptible to Ciprofloxacin (10 μg), tarivid (10 μg) and streptomycin (30 μg); and moderately- to poorly sensitive to the other antibiotics used in the study. In conclusion female diabetics were at a higher risk for UTIs that than males (p=0.000) and low educational level/social class was also a risk factor (p=0.04) when compared to subjects of higher educational level/ social class.

Details

ISSN :
25367153
Volume :
7
Database :
OpenAIRE
Journal :
Sokoto Journal of Medical Laboratory Science
Accession number :
edsair.doi.dedup.....ca65e64a563077d387f4a8e88fd759f4
Full Text :
https://doi.org/10.4314/sokjmls.v7i3.10