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Natural History of Atherosclerosis and Abdominal Aortic Intima-Media Thickness: Rationale, Evidence, and Best Practice for Detection of Atherosclerosis in the Young
- Source :
- Journal of Clinical Medicine, Vol 8, Iss 8, p 1201 (2019), Journal of Clinical Medicine
- Publication Year :
- 2019
- Publisher :
- MDPI AG, 2019.
-
Abstract
- Atherosclerosis underlies most myocardial infarctions and ischemic strokes. The timing of onset and the rate of progression of atherosclerosis differ between individuals and among arterial sites. Physical manifestations of atherosclerosis may begin in early life, particularly in the abdominal aorta. Measurement of the abdominal aortic intima-media thickness by external ultrasound is a non-invasive methodology for quantifying the extent and severity of early atherosclerosis in children, adolescents, and young adults. This review provides an evidence-based rationale for the assessment of abdominal aortic intima-media thickness—particularly as an age-appropriate methodology for studying the natural history of atherosclerosis in the young in comparison to other methodologies—establishes best practice methods for assessing abdominal aortic intima-media thickness, and identifies key gaps in the literature, including those that will identify the clinical relevance of this measure.
- Subjects :
- medicine.medical_specialty
lcsh:Medicine
Review
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
medicine.artery
Internal medicine
medicine
Clinical significance
030212 general & internal medicine
Young adult
aorta
atherosclerosis
intima-media thickness
ultrasound
Aorta
business.industry
Ischemic strokes
Abdominal aorta
lcsh:R
General Medicine
Natural history
Aortic intima
Intima-media thickness
Cardiology
cardiovascular system
business
Subjects
Details
- Language :
- English
- ISSN :
- 20770383
- Volume :
- 8
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Medicine
- Accession number :
- edsair.doi.dedup.....cabbee19752cfae68945410c888679a4