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TAC y PET/TC con 18-FDG para evaluar la respuesta al tratamiento en linfoma de Hodgkin y no Hodgkin
- Source :
- Gaceta medica de Mexico. 155(4)
- Publication Year :
- 2019
-
Abstract
- espanolIntroduccion: La evaluacion de la respuesta al tratamiento de linfoma se basa en estudios de imagen. Objetivo: Correlacionar la evaluacion de la respuesta al tratamiento de linfoma mediante tomografia axial computarizada (TAC) y tomografia por emision de positrones/tomografia computarizada (PET/TC). Metodo: Estudio observacional transversal en el que se revisaron expedientes de pacientes con linfoma en vigilancia mediante TAC y PET/TC. Resultados: La poblacion de estudio estuvo constituida por 43 pacientes con edad media de 32.7 ± 22.4 anos; 26 (60.5 %) tenian diagnostico de linfoma de Hodgkin y 17 (9.5 %), de linfoma no Hodgkin. Por TAC se diagnosticaron 34 (79.1 %) con enfermedad y nueve (20.9 %) sin enfermedad. El criterio para evaluar la respuesta fue la experiencia del medico imagenologo en 39 (90.7 %) y RECIST 1.1 en cuatro (9.3 %). Por PET/TC con 18-FDG se diagnostico falta de respuesta al tratamiento o respuesta parcial-recurrencia en 32 pacientes (74.4 %) y con respuesta al tratamiento en 11 (25.6 %); con los criterios PERCIST en 13 (30.2 %) y con los de Deuaville en 30 (69.8 %). Al comparar el diagnostico por TAC contra PET/TC, de 11 pacientes con respuesta total, tres tuvieron diagnostico tomografico similar. De los 34 pacientes con datos de enfermedad diagnosticados por tomografia, 26 tuvieron resultados similares por PET/TC con 18-FDG (p = 0.54). Conclusion: El valor de la respuesta al tratamiento por TAC en linfoma no concuerda con el obtenido mediante PET/TC con 18-FDG. EnglishIntroduction: The assessment of lymphoma response to treatment is based on imaging studies. Objective: To correlate the assessment of lymphoma treatment response by computed tomography (CT) and by positron emission tomography/computed tomography (PET/CT). Method: Cross-sectional, observational study, where records of patients with lymphoma under surveillance by CT and PET/CT were reviewed. Results: The study population consisted of 43 patients with a mean age of 32.7 ± 22.4 years; 26 (60.5 %) had a diagnosis of Hodgkin’s lymphoma and 17 (9.5 %) had non-Hodgkin lymphoma. By CT, 34 (79.1 %) were diagnosed with disease and nine (20.9 %) without disease. The criteria used to assess the response was radiologist experience in 39 (90.7 %) and RECIST 1.1 criteria in four (9.3 %). The diagnosis by 18-FDG PET/CT was no response to treatment or partial response-recurrence in 32 (74.4 %) and response to treatment in 11 (25.6 %); with PERCIST criteria in 13 (30.2 %) and Deuaville criteria in 30 (69.8 %). When the diagnosis by CT versus 18-FDG PET/CT was compared, out of 11 patients with complete response on PET/CT, three had a similar CT diagnosis. Of the 34 patients with data consistent disease diagnosed by CT, 26 had similar results by 18-FDG PET/CT (p = 0.54). Conclusion: The value of lymphoma treatment response on CT does not agree with that obtained by 18-FDG PET/CT.
- Subjects :
- Adult
Male
Treatment response
Adolescent
Computed tomography
Young Adult
Fluorodeoxyglucose F18
Positron Emission Tomography Computed Tomography
medicine
Humans
Ct diagnosis
Child
Complete response
Aged
medicine.diagnostic_test
business.industry
Lymphoma, Non-Hodgkin
Mean age
General Medicine
Middle Aged
medicine.disease
Response to treatment
Hodgkin Disease
Lymphoma
Cross-Sectional Studies
Treatment Outcome
Positron emission tomography
Female
business
Nuclear medicine
Tomography, X-Ray Computed
Subjects
Details
- ISSN :
- 00163813
- Volume :
- 155
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Gaceta medica de Mexico
- Accession number :
- edsair.doi.dedup.....cb37842f32d75ab4014fcfd85b444afe