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Pulmonary Findings of [18F]FDG PET/CT Images on Asymptomatic COVID-19 Patients
- Source :
- Pathogens, Vol 10, Iss 839, p 839 (2021)
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- During the coronavirus disease 2019 (COVID-19) pandemic, several case studies demonstrated that many asymptomatic patients with COVID-19 underwent fluorine-18 fluorodeoxyglucose ([18F]FDG) positron emission tomography/computed tomography (PET/CT) examination for various indications. However, there is a lack of literature to characterize the pattern of [18F]FDG PET/CT imaging on asymptomatic COVID-19 patients. Therefore, a systematic review to analyze the pulmonary findings of [18F]FDG PET/CT on asymptomatic COVID-19 patients was conducted. This systematic review was performed under the guidelines of PRISMA. PubMed, Medline, and Web of Science were used to search for articles for this review. Articles with the key words: “asymptomatic”, “COVID-19”, “[18F]FDG PET/CT”, and “nuclear medicine” were searched for from 1 January 2020 to 20 May 2021. Thirty asymptomatic patients with COVID-19 were included in the eighteen articles. These patients had a mean age of 62.25 ± 14.85 years (male: 67.71 ± 12.00; female: 56.79 ± 15.81). [18F]FDG-avid lung lesions were found in 93.33% (28/30) of total patients. The major lesion was [18F]FDG-avid multiple ground-glass opacities (GGOs) in the peripheral or subpleural region in bilateral lungs, followed by the consolidation. The intensity of [18F]FDG uptake in multiple GGOs was 5.605 ± 2.914 (range from 2 to 12) for maximal standardized uptake value (SUVmax). [18F]FDG-avid thoracic lymph nodes (LN) were observed in 40% (12/40) of the patients. They mostly appeared in both mediastinal and hilar regions with an SUVmax of 5.8 ± 2.93 (range from 2.5 to 9.6). The [18F]FDG uptake was observed in multiple GGOs, as well as in the mediastinal and hilar LNs. These are common patterns in PET/CT of asymptomatic patients with COVID-19.
- Subjects :
- Microbiology (medical)
Coronavirus disease 2019 (COVID-19)
Standardized uptake value
Asymptomatic
asymptomatic patients
030218 nuclear medicine & medical imaging
Lesion
03 medical and health sciences
0302 clinical medicine
medicine
Immunology and Allergy
nuclear medicine
[18F]FDG PET/CT
Molecular Biology
Fluorodeoxyglucose
Lung
General Immunology and Microbiology
medicine.diagnostic_test
business.industry
COVID-19
Infectious Diseases
medicine.anatomical_structure
Positron emission tomography
030220 oncology & carcinogenesis
Medicine
Fdg pet ct
medicine.symptom
Nuclear medicine
business
medicine.drug
Subjects
Details
- ISSN :
- 20760817
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Pathogens
- Accession number :
- edsair.doi.dedup.....cb5b443cc1dc9541b02ee66d9b9d371e
- Full Text :
- https://doi.org/10.3390/pathogens10070839