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IgA Vasculitis With Nephritis (Henoch−Schönlein Purpura) in a COVID-19 Patient

Authors :
Alejandro Pascual Martin
Verónica Mercado Valdivia
Juan Carlos Herrero Berrón
María Sánchez Sánchez
Aniana Oliet Pala
Marina Alonso Riaño
Karen Daniela Galindo Romo
Carolina Lentisco Ramírez
Carmen Mon
Andrea Suso
Nicolás Silvestre Torner
Irene Onate Alonso
Olimpia Ortega Marcos
Milagros Ortiz Librero
Rosa Elena Camacho Juárez
Source :
Kidney International Reports
Publication Year :
2020
Publisher :
Elsevier BV, 2020.

Abstract

In December 2019, a series of pneumonia cases of unknown etiology, which were epidemiologically linked to a seafood market, was reported in Wuhan, Hubei province, China. The disease has rapidly spread around the world, becoming a global pandemic. A coronavirus, which was named 2019 novel coronavirus (2019-nCov), was isolated from respiratory tract samples1 and later identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The name of the disease was officially changed to coronavirus disease 2019 (COVID-19). Pulmonary involvement with alveolar damage and acute respiratory failure has been the most remarkable clinical condition of COVID-19 patients. However, there is increasing evidence that this virus also affects other organs, kidney injury being relatively common in this infection and associated with an increased mortality rate.2 In a large prospective cohort of 701 COVID-19 patients in China, 44% had proteinuria and 27% had hematuria on admission. During hospitalization, 5.1% of them developed acute kidney injury.2 We report a patient who developed systemic symptoms and renal involvement after being hospitalized because of a COVID-19 infection. A mesangial proliferation and IgA deposits in the glomeruli were seen on the kidney biopsy specimen.

Details

ISSN :
24680249
Volume :
5
Database :
OpenAIRE
Journal :
Kidney International Reports
Accession number :
edsair.doi.dedup.....cb617c23afcf91ecbb460a6230c23131
Full Text :
https://doi.org/10.1016/j.ekir.2020.08.016