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IgA Vasculitis With Nephritis (Henoch−Schönlein Purpura) in a COVID-19 Patient
- Source :
- Kidney International Reports
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- In December 2019, a series of pneumonia cases of unknown etiology, which were epidemiologically linked to a seafood market, was reported in Wuhan, Hubei province, China. The disease has rapidly spread around the world, becoming a global pandemic. A coronavirus, which was named 2019 novel coronavirus (2019-nCov), was isolated from respiratory tract samples1 and later identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The name of the disease was officially changed to coronavirus disease 2019 (COVID-19). Pulmonary involvement with alveolar damage and acute respiratory failure has been the most remarkable clinical condition of COVID-19 patients. However, there is increasing evidence that this virus also affects other organs, kidney injury being relatively common in this infection and associated with an increased mortality rate.2 In a large prospective cohort of 701 COVID-19 patients in China, 44% had proteinuria and 27% had hematuria on admission. During hospitalization, 5.1% of them developed acute kidney injury.2 We report a patient who developed systemic symptoms and renal involvement after being hospitalized because of a COVID-19 infection. A mesangial proliferation and IgA deposits in the glomeruli were seen on the kidney biopsy specimen.
- Subjects :
- medicine.medical_specialty
Henoch-Schonlein purpura
IgA Vasculitis
SARS-CoV-2
business.industry
COVID-19
medicine.disease
medicine.disease_cause
Gastroenterology
Article
Henoch-Schönlein
Pneumonia
IgA vasculitis
Nephrology
Internal medicine
cytokine storm
medicine
Etiology
Mesangial proliferative glomerulonephritis
postinfectious glomerulonephritis
Diffuse alveolar damage
business
Nephritis
Coronavirus
Subjects
Details
- ISSN :
- 24680249
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Kidney International Reports
- Accession number :
- edsair.doi.dedup.....cb617c23afcf91ecbb460a6230c23131
- Full Text :
- https://doi.org/10.1016/j.ekir.2020.08.016