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Determinants of the Extremes of Outcome in Schizophrenia
- Source :
- British Journal of Psychiatry. 167:604-609
- Publication Year :
- 1995
- Publisher :
- Royal College of Psychiatrists, 1995.
-
Abstract
- BackgroundAlthough poor prognosis has been considered a defining characteristic of schizophrenia, long-term studies show marked heterogeneity of outcome.MethodAssessments of positive and negative symptoms, premorbid and current IQ, and months of in-patient care made in an outcome study of 342 schizophrenic patients were categorised by severity. Determinants of these categorisations were sought from the historical variables available, using analysis of variance. Vignettes of patients with the best and worst symptomatic outcomes were then compared.ResultsNegative symptoms were associated with early onset, male sex and poor academic record. Positive symptoms were associated with occupational decline. Cognitive decline was associated with occupational variables, and in-patient care with academic and occupational variables. The vignettes showed that good outcome was associated with family psychiatric history and poor outcome with unavailability of family history.ConclusionsThe findings support the view that the most malignant form of schizophrenia is neurodevelopmental, but poor outcome was clearly associated with family fragmentation.
- Subjects :
- Adult
Male
medicine.medical_specialty
Psychosis
Outcome (game theory)
03 medical and health sciences
0302 clinical medicine
Psychiatric history
medicine
Humans
Family
030212 general & internal medicine
Cognitive decline
Family history
Psychiatry
Psychiatric Status Rating Scales
Rehabilitation, Vocational
Prognosis
medicine.disease
030227 psychiatry
Psychiatry and Mental health
Treatment Outcome
Schizophrenia
Educational Status
Female
Schizophrenic Psychology
Analysis of variance
Age of onset
Psychology
Follow-Up Studies
Clinical psychology
Subjects
Details
- ISSN :
- 14721465 and 00071250
- Volume :
- 167
- Database :
- OpenAIRE
- Journal :
- British Journal of Psychiatry
- Accession number :
- edsair.doi.dedup.....cb6c56fee14aed770d7272eafb59846e
- Full Text :
- https://doi.org/10.1192/bjp.167.5.604