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Development of Group A streptococcal vaccines: an unmet global health need
- Source :
- Expert review of vaccines. 15(2)
- Publication Year :
- 2015
-
Abstract
- Group A Streptococcus (GAS) infections are a significant global cause of morbidity and mortality. GAS diseases disproportionally affect those living in conditions characterized by poverty and social injustice, in both developing countries and in marginalized populations of industrialized nations. In Australia and New Zealand, GAS-associated Acute Rheumatic Fever (ARF) is a major cause of health inequality disproportionally affecting indigenous children. Recognition of these inequalities by the governments of Australia and New Zealand has resulted in the formation of a Trans-Tasman Coalition to Advance New Vaccines for group A Streptococcus (CANVAS). This review provides an update on the current status of GAS vaccine development, and describes global efforts by CANVAS and others to accelerate the development of GAS vaccines.
- Subjects :
- 0301 basic medicine
Economic growth
Inequality
Streptococcus pyogenes
media_common.quotation_subject
Immunology
Developing country
Indigenous
03 medical and health sciences
0302 clinical medicine
Streptococcal Vaccines
Streptococcal Infections
Drug Discovery
Global health
Medicine
Humans
030212 general & internal medicine
media_common
Pharmacology
Poverty
business.industry
Australia
Health equity
030104 developmental biology
Molecular Medicine
business
Developed country
New Zealand
Subjects
Details
- ISSN :
- 17448395
- Volume :
- 15
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Expert review of vaccines
- Accession number :
- edsair.doi.dedup.....cc2bff4a8b1c8776f5bfc48fa79ca682