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Clinical Presentation and Outcome in a Contemporary Cohort of Patients With Acute Myocarditis: Multicenter Lombardy Registry

Authors :
Cristina Giannattasio
Riccardo Mantovani
Aurelia Grosu
Giovanni Battista Perego
Paola Sormani
Antonello Gavazzi
Giovanni Peretto
Daniele Briguglia
Marisa Varrenti
Marco Metra
Carlo Campana
Maria Frigerio
Stefania Colombo
Claudia Raineri
Jeness Campodonico
Salvatore I. Caico
Carlo Lombardi
Silvia Guglielmetto
Manlio Cipriani
Daniela Pini
Enrico Ammirati
Fabrizio Oliva
Fabrizio Morandi
Michele Senni
Piergiuseppe Agostoni
Claudio Moro
A. Ciro
Armando Belloni
Laura Scelsi
Valentina Carubelli
Andrea Mortara
Annalisa Turco
Paolo G. Camici
Patrizia Pedrotti
Antonio Mafrici
Cristina Conca
Alberto Maestroni
Giuseppe Di Tano
Ammirati, E
Cipriani, M
Moro, C
Raineri, C
Pini, D
Sormani, P
Mantovani, R
Varrenti, M
Pedrotti, P
Conca, C
Mafrici, A
Grosu, A
Briguglia, D
Guglielmetto, S
Battista Perego, G
Colombo, S
Caico, S
Giannattasio, C
Maestroni, A
Carubelli, V
Metra, M
Lombardi, C
Campodonico, J
Agostoni, P
Peretto, G
Scelsi, L
Turco, A
Di Tano, G
Campana, C
Belloni, A
Morandi, F
Mortara, A
CirĂ², A
Senni, M
Gavazzi, A
Frigerio, M
Oliva, F
Camici, P
Source :
Circulation. 138(11)
Publication Year :
2018

Abstract

Background: There is controversy about the outcome of patients with acute myocarditis (AM), and data are lacking on how patients admitted with suspected AM are managed. We report characteristics, in-hospital management, and long-term outcome of patients with AM based on a retrospective multicenter registry from 19 Italian hospitals. Methods: A total of 684 patients with suspected AM and recent onset of symptoms (70 years of age and those >50 years of age without coronary angiography were excluded. The final study population comprised 443 patients (median age, 34 years; 19.4% female) with AM diagnosed by either endomyocardial biopsy or increased troponin plus edema and late gadolinium enhancement at cardiac magnetic resonance. Results: At presentation, 118 patients (26.6%) had left ventricular ejection fraction P P P =0.18). After a median time of 196 days, 200 patients had follow-up cardiac magnetic resonance, and 8 of 55 (14.5%) with complications at presentation had left ventricular ejection fraction Conclusions: In this contemporary study, overall serious adverse events after AM were lower than previously reported. However, patients with left ventricular ejection fraction

Details

ISSN :
15244539
Volume :
138
Issue :
11
Database :
OpenAIRE
Journal :
Circulation
Accession number :
edsair.doi.dedup.....cd05a0b321ff8e12f68775ce9caf7ce8