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Endoscopic ultrasound elastography: the first step towards virtual biopsy? Preliminary results in 49 patients
- Source :
- Endoscopy. 38(4)
- Publication Year :
- 2006
-
Abstract
- Background and Study Aims: It is well known that some diseases, such as cancer, lead to changes in the hardness of tissue. Sonoelastography, a technique that allows the elasticity of tissue to be assessed during ultrasound examination, provides the ultrasonographer with important additional information that can be used for diagnosis. The aim of this study was to evaluate the ability of endoscopic ultrasound elastography to differentiate between benign and malignant pancreatic masses and lymph nodes.Patients and Methods: During a 12-month period, 49 patients underwent endoscopic ultrasound (EUS) examinations with elastography, conducted by a single endoscopist. Twenty-four patients underwent evaluation of a pancreatic mass (mean diameter 24.7 ± 11.1mm) and 25 underwent evaluation of 31 lymph nodes. The mean diameter of the lymph nodes was 19.7 ± 8.6 mm, and they were found in the cervical area (n = 3), mediastinum (n = 17), celiac arterial trunk region (n = 5), and aortocaval region (n = 6).Results: The sonoelastography images of pancreatic masses were interpreted as benign in four cases and malignant in 20. The sensitivity and specificity of sonoelastography in the diagnosis of malignant lesions were 100 % and 67 %, respectively. The sonoelastography images of the lymph nodes were interpreted as showing malignancy in 22 cases, benign conditions in seven, and indeterminate status in two. The sensitivity and specificity of sonoelastography for evaluating malignant lymph-node invasion were 100 % and 50 %, respectively.Conclusions: EUS elastography is potentially capable of further defining the tissue characteristics of benign and malignant lesions but specifity has to be improved. It can be used to guide biopsy sampling for diagnosis.
- Subjects :
- Endoscopic ultrasound
Adult
Male
medicine.medical_specialty
Adolescent
Biopsy, Fine-Needle
Sonoelastography
Malignancy
Sensitivity and Specificity
Endosonography
Diagnosis, Differential
Biopsy
Pancreatic mass
medicine
Humans
Aged
Neoplasm Staging
Retrospective Studies
Aged, 80 and over
medicine.diagnostic_test
business.industry
Ultrasound
Gastroenterology
Mediastinum
Middle Aged
medicine.disease
Pancreatic Neoplasms
medicine.anatomical_structure
Female
Elastography
Radiology
Lymph Nodes
business
Subjects
Details
- ISSN :
- 0013726X
- Volume :
- 38
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Endoscopy
- Accession number :
- edsair.doi.dedup.....ce4c5b30104f3a1d49190e386d3300c3