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Transcutaneous Electrical Nerve Stimulation Regulates Organ Blood Flow and Apoptosis during Controlled Hypotension in Dogs
- Source :
- PLoS ONE, PLoS ONE, Vol 9, Iss 4, p e94368 (2014)
- Publication Year :
- 2014
- Publisher :
- Public Library of Science, 2014.
-
Abstract
- Transcutaneous electrical nerve stimulation (TENS) is commonly used in clinical practice for alleviating pains and physiological disorders. It has been reported that TENS could counteract the ischemic injury happened in some vital organs. To determine the protective effect of TENS on internal organs during CH in dogs, target hypotension was maintained for 60 min at 50% of the baseline mean arterial pressure (MAP). The perfusion to the brain, liver, stomach, and kidney was recorded and apoptosis within these organs was observed. Results showed that when arriving at the target MAP, and during the maintaining stage for 10 min, perfusion to the stomach and liver in the CH+TENS group was much higher than in the CH group (P
- Subjects :
- Male
lcsh:Medicine
Apoptosis
Hypotension, Controlled
law.invention
Cell Signaling
law
Anesthesiology
Molecular Cell Biology
Anti-Apoptotic Signaling
Medicine and Health Sciences
lcsh:Science
Kidney
Multidisciplinary
TUNEL assay
Stomach
Animal Models
medicine.anatomical_structure
Organ Specificity
Anesthesia
Transcutaneous Electric Nerve Stimulation
Perfusion
Research Article
Signal Transduction
medicine.medical_specialty
Mean arterial pressure
Cognitive Neuroscience
Pain
Surgical and Invasive Medical Procedures
Research and Analysis Methods
Transcutaneous electrical nerve stimulation
Model Organisms
Dogs
Complementary and Alternative Medicine
Internal medicine
medicine
In Situ Nick-End Labeling
Pain Management
Animals
Arterial Pressure
business.industry
lcsh:R
Biology and Life Sciences
Blood flow
Cell Biology
Endocrinology
Blood pressure
Regional Blood Flow
lcsh:Q
business
Acupuncture Points
Neuroscience
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 9
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....ce8219fd385c8e0c4d7bb502317af474