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Improved Models of Coalescence Ages of Y-DNA Haplogroups
- Source :
- Genes, Volume 12, Issue 6, Genes, Vol 12, Iss 862, p 862 (2021)
- Publication Year :
- 2021
- Publisher :
- Multidisciplinary Digital Publishing Institute, 2021.
-
Abstract
- Databases of commercial DNA-testing companies now contain more customers with sequenced DNA than any completed academic study, leading to growing interest from academic and forensic entities. An important result for both these entities and the test takers themselves is how closely two individuals are related in time, as calculated through one or more molecular clocks. For Y-DNA, existing interpretations of these clocks are insufficiently accurate to usefully measure relatedness in historic times. In this article, I update the methods used to calculate coalescence ages (times to most-recent common ancestor, or TMRCAs) using a new, probabilistic statistical model that includes Y-SNP, Y-STR and ancilliary historical data, and provide examples of its use.
- Subjects :
- Male
0301 basic medicine
Computer science
Human Y-chromosome DNA haplogroup
030105 genetics & heredity
QH426-470
computer.software_genre
Article
Time
time estimation
03 medical and health sciences
Mutation Rate
Time estimation
Direct-To-Consumer Screening and Testing
Genetics
Humans
Genetic Testing
Coalescence (chemistry)
Molecular clock
QH426
Genetics (clinical)
Ancestor
Chromosomes, Human, Y
Polymorphism, Genetic
Models, Genetic
business.industry
Probabilistic logic
molecular clock
Statistical model
Pedigree
030104 developmental biology
Haplotypes
male history
Artificial intelligence
business
computer
human Y chromosome
Natural language processing
Microsatellite Repeats
Subjects
Details
- Language :
- English
- ISSN :
- 20734425
- Database :
- OpenAIRE
- Journal :
- Genes
- Accession number :
- edsair.doi.dedup.....ce8bc1edbd3fc223bb28e620e4c59784
- Full Text :
- https://doi.org/10.3390/genes12060862