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Exploring links between vitamin D deficiency and COVID-19
- Source :
- PLoS Pathogens, PLoS Pathogens, Vol 16, Iss 9, p e1008874 (2020)
- Publication Year :
- 2020
- Publisher :
- Public Library of Science, 2020.
-
Abstract
- Coronavirus Disease 2019 (COVID-19) pandemic remains a major public health threat in most countries. The causative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can lead to acute respiratory distress syndrome and result in mortality in COVID-19 patients. Vitamin D is an immunomodulator hormone with established effectiveness against various upper respiratory infections. Vitamin D can stall hyper-inflammatory responses and expedite healing process of the affected areas, primarily in the lung tissue. Thus, there are ecological and mechanistic reasons to promote exploration of vitamin D action in COVID-19 patients. As no curative drugs are available currently for COVID-19, we feel that the potential of vitamin D to alter the course of disease severity needs to be investigated. Clinical studies may be undertaken to address the value of vitamin D supplementation in deficient, high-risk COVID-19 patients.
- Subjects :
- Viral Diseases
Critical Care and Emergency Medicine
Pulmonology
Physiology
Organic chemistry
Pearls
Medical Conditions
Immune Physiology
Pandemic
Medicine and Health Sciences
Biology (General)
Vitamin D
Immune Response
Acute Respiratory Distress Syndrome
Respiratory Distress Syndrome
0303 health sciences
Innate Immune System
030302 biochemistry & molecular biology
Nutritional Deficiencies
Vitamins
Physical sciences
Chemistry
Infectious Diseases
Micronutrient Deficiencies
Cytokines
Coronavirus Infections
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
QH301-705.5
Pneumonia, Viral
Immunology
Microbiology
Virus
vitamin D deficiency
Betacoronavirus
03 medical and health sciences
Chemical compounds
Respiratory Disorders
Immune system
Respiratory Failure
Virology
Organic compounds
Genetics
medicine
Vitamin D and neurology
Humans
Pandemics
Molecular Biology
030304 developmental biology
Nutrition
Vitamin D deficiency
Biology and life sciences
SARS-CoV-2
business.industry
Public health
COVID-19
Covid 19
RC581-607
Molecular Development
medicine.disease
Immune System
Dietary Supplements
Respiratory Infections
Parasitology
Immunologic diseases. Allergy
business
Hormone
Developmental Biology
Subjects
Details
- Language :
- English
- ISSN :
- 15537374 and 15537366
- Volume :
- 16
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- PLoS Pathogens
- Accession number :
- edsair.doi.dedup.....cea3013f1a06bcca1a5297c4b971a84d