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Human milk 3'-Sialyllactose is positively associated with language development during infancy
- Source :
- The American Journal of Clinical Nutrition
- Publication Year :
- 2020
-
Abstract
- Background Genetic polymorphisms leading to variations in human milk oligosaccharide (HMO) composition have been reported. Alpha-Tetrasaccharide (A-tetra), an HMO, has been shown to only be present (>limit of detection; A-tetra+) in the human milk (HM) of women with blood type A, suggesting genetic origins determining the presence or absence (A-tetra-) of A-tetra in HM. Objectives This study aimed to determine whether associations exist between HMO concentrations and cognitive development, and whether the associations vary between A-tetra+ and A-tetra- groups in children (
- Subjects :
- 0301 basic medicine
Adult
medicine.medical_specialty
Composite score
Medicine (miscellaneous)
Oligosaccharides
Language Development
AcademicSubjects/MED00160
03 medical and health sciences
Typically developing
AcademicSubjects/MED00060
Primary outcome
breastfed infants
Internal medicine
Receptive language
Medicine
Humans
early cognitive development
sialyllactose
030109 nutrition & dietetics
Nutrition and Dietetics
language
Milk, Human
business.industry
Mullen Scales of Early Learning
Infant
human milk
Cognition
Growth, Development, and Pediatrics
Language development
Original Research Communications
random linear mixed effects model
030104 developmental biology
Breast Feeding
Child, Preschool
Mixed effects
Female
human milk oligosaccharides
business
Breast feeding
Subjects
Details
- ISSN :
- 19383207
- Volume :
- 114
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- The American journal of clinical nutrition
- Accession number :
- edsair.doi.dedup.....cea4f47a01733e5ea8133bde9616c500