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A High Neutrophil-to-Lymphocyte Ratio Is Associated with Recovery from Ramsay Hunt Syndrome

Authors :
Seung Geun Yeo
Jong Ha Lee
Sung Hwa Dong
Jae Yong Byun
Moon Suh Park
Junyang Jung
Sang Hoon Kim
Yunsoo Soh
Source :
ORL. 81:130-137
Publication Year :
2019
Publisher :
S. Karger AG, 2019.

Abstract

Background: Prediction of the severity and outcomes of Ramsay Hunt syndrome (RHS) is difficult. Objectives: The aim of this study was to evaluate the predictive power of the neutrophil-to-lymphocyte ratio (NLR) for the severity and outcomes of RHS. Material and Methods: From 2007 to 2017, a retrospective study of 102 hospitalized patients with RHS was conducted. The degree of paralysis was assessed by determining the House-Brackmann (H-B) grade. Obesity, hypertension, and diabetes mellitus were assessed, and the blood NLR and platelet-to-lymphocyte ratio were determined. The patients received steroids and antivirals, and were followed in the outpatient department at 1, 4, 12, and 24 weeks. Results: The H-B grade of the high-NLR group was significantly higher than that of the normal-NLR group (p = 0.039), and the probability of complete recovery was significantly lower in the high-NLR group (p = 0.048). Conclusions: Patients with RHS who have an elevated NLR have poor outcomes in terms of the H-B grade. Therefore, the NLR may be useful for evaluating the prognosis of patients with RHS.

Details

ISSN :
14230275 and 03011569
Volume :
81
Database :
OpenAIRE
Journal :
ORL
Accession number :
edsair.doi.dedup.....cfb3694bf4b0d8a49c96011632c483ab