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Novel coronavirus (SARS‐CoV‐2) infection in a renal transplant recipient: Case report

Authors :
Hongtao Liu
Jizhou Wang
Lei Li
Lianxin Liu
Ziqin Yao
Wenyuan Li
Aizong Shen
Lei Liu
Shengyu Zhang
Ling Ning
Björn Nashan
Desheng Zhao
Source :
American Journal of Transplantation
Publication Year :
2020
Publisher :
John Wiley and Sons Inc., 2020.

Abstract

An ongoing outbreak of pneumonia associated with the severe acute respiratory coronavirus 2 (SARS-CoV-2) started in Wuhan, China, with cases now confirmed in multiple countries. The clinical course of patients remains to be fully characterized, clinical presentation ranges from asymptomatic infection to acute respiratory distress syndrome and acute renal failure, and no pharmacological therapies of proven efficacy yet exist. We report a case of SARS-CoV-2 infection in a renal transplant recipient with excellent outcome. This case states the importance of close monitoring of the concentration of cyclosporine in patients treated with lopinavir/ritonavir; the routine treatment of corticosteroid can be continued. This is a rare report of SARS-CoV-2 infection in a renal transplant recipient. Further data are needed to achieve better understanding of the impact of immunosuppressive therapy on the clinical presentation, severity, and outcome of SARS-CoV-2 infections in solid organ transplant recipients.

Details

Language :
English
ISSN :
16006143 and 16006135
Database :
OpenAIRE
Journal :
American Journal of Transplantation
Accession number :
edsair.doi.dedup.....cfcf5966222f9d3b8a9c5575354b5dd2