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First nation-wide estimation of tobacco consumption in Spain using wastewater-based epidemiology

Authors :
Miren López de Alda
José Benito Quintana
Yolanda Valcárcel
Ester López-García
Alberto Celma
María Rosende
Rafael Cela
Félix Hernández
Rosa Maria Marcé
Lubertus Bijlsma
Maitane Olivares
Cristina Postigo
Rosa Montes
Andreu Rico
Vicente Andreu
Eva Pocurull
Rosario Rodil
Iria González-Mariño
Yolanda Picó
Universidade de Santiago de Compostela. Departamento de Química Analítica, Nutrición e Bromatoloxía
Universidade de Santiago de Compostela. Instituto de Investigación e Análises Alimentarias
López De Alda, Miren
Postigo, Cristina
López De Alda, Miren [0000-0002-9347-2765]
Postigo, Cristina [0000-0002-7344-7044]
Source :
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela, Universidad de Santiago de Compostela (USC), Repositori Universitat Jaume I, Universitat Jaume I, Digital.CSIC. Repositorio Institucional del CSIC, instname, Repositorio Institucional del Instituto IMDEA Agua, Instituto IMDEA Agua (IMDEA AGUA), Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Publication Year :
2020
Publisher :
Elsevier, 2020.

Abstract

Wastewater-based epidemiology (WBE) has become a very useful tool to monitor a population's drug consumption or exposure to environmental and food contaminants. In this work, WBE has been applied to estimate tobacco consumption in seven Spanish regions. To this end, 24 h composite wastewater samples were taken daily for one week in 17 wastewater treatment plants, covering altogether a population of ca. 6 million inhabitants. The samples were treated by enzymatic deconjugation and the wastewater content of two human-specific nicotine metabolites (namely, cotinine and trans-3′-hydroxycotinine) was measured to estimate the daily consumption of nicotine. The population-weighted average nicotine consumption in the seven analyzed regions was 2.2 g/(day∙1000 inh.), without any daily pattern. This average estimated nicotine consumption value agreed with the value derived from official tobacco sales data. Differences in consumption among the seven studied regions were found, being Galicia, the region with the lowest rate, and the Basque Country and Catalonia those with the highest rates. However, no conclusive correlation was found between those values and the prevalence data taken from two different national surveys, nor sociodemographic and health data. This study demonstrates that this tool can complement other indicators in order to accurately assess tobacco consumption rates at regional and national levels and provides the most extensive application of the approach in the Spanish territory.<br />Financial support This study was supported by MINECO/AEI projects (CTM2016-81935-REDT, CTM2017-84763-C3-2-R, CTM2017-84763-C3-1-R, CTM2017-84763-C3-3-R), MICINN project (CEX2018-000794-S), Galician Council of Culture, Education and Universities (ED481D 2017/003 and ED431C2017/36), cofunded by FEDER/ERDF.

Details

Database :
OpenAIRE
Journal :
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela, Universidad de Santiago de Compostela (USC), Repositori Universitat Jaume I, Universitat Jaume I, Digital.CSIC. Repositorio Institucional del CSIC, instname, Repositorio Institucional del Instituto IMDEA Agua, Instituto IMDEA Agua (IMDEA AGUA), Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Accession number :
edsair.doi.dedup.....cfdf654319c5c341d2341d55bf992148