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Proteomics imaging and the kidney
- Publication Year :
- 2013
- Publisher :
- Springer, 2013.
-
Abstract
- Matrix-assisted laser desorption/ionization (MALDI) and mass spectrometry (MS) imaging are advanced technologies capable of revealing the spatial distribution of different molecules--e.g., drugs and their metabolites, endogenous lipids and complex peptides/proteins--directly in tissue specimens at the same time. Information obtained regarding tissues by MALDI profiling/imaging analysis can be correlated with other MS-based techniques, auxiliary imaging technologies and routine immunohistochemical stainings. In this review we describe the MALDI profiling/imaging technologies, providing examples of their application in kidney research.
- Subjects :
- Proteomics
Pathology
medicine.medical_specialty
Mass spectrometry
Kidney
01 natural sciences
Mass spectrometry imaging
Protein expression
03 medical and health sciences
medicine
Animals
Humans
030304 developmental biology
0303 health sciences
business.industry
Animal
Settore BIO/12
010401 analytical chemistry
Proteomic
3. Good health
0104 chemical sciences
Imaging analysis
Molecular Imaging
Biochemistry
Nephrology
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Molecular imaging
business
Human
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....cfe644f63dd7dd7c922044cedbac6ced