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Immunotherapy 'Shock' a case series of PD-L1 100% and pembrolizumab first-line treatment

Authors :
Chong Bai
Evaggelia Athanasiou
Paul Zarogoulidis
Aggeliki Rapti
Haidong Huang
Dimitrios Drougas
Dimitrios Paliouras
Wolfgang Hohenforst-Schmidt
Georgia Trakada
Dimitrios Hatzibougias
Lemonia Veletza
Christoforos Kosmidis
Theodora Tsiouda
Nikolaos Barbetakis
Anastasios Kallianos
Source :
Respiratory Medicine Case Reports, Vol 22, Iss C, Pp 197-202 (2017), Respiratory Medicine Case Reports
Publication Year :
2017
Publisher :
Elsevier, 2017.

Abstract

In this decade a “bloom” of novel therapies has been observed for non-small cell lung cancer. We have new tools for the diagnosis of lung cancer and also we can re-biospy easier than before in different lesions and obtain tissue samples in order to investigate whether a patient can receive new targeted therapies. Immunotherapy has been well established previously for other forms of cancer, and nowadays it is also available for lung cancer. There are two immunotherapies for now nivolumab and pembrolizumab which can be administered as second line treatment, the second can also be administered as first-line if there is a programmed death-ligand 1 ≥50% expression.

Details

Language :
English
ISSN :
22130071
Volume :
22
Database :
OpenAIRE
Journal :
Respiratory Medicine Case Reports
Accession number :
edsair.doi.dedup.....cff5916170ca82ec3ab9504d7372d5f2