The testicular morphology of individuals exposed to dibromochloropropane

Testicular biopsies from 10 individuals with histories of exposure to 1,2-dibromo-3-chloropropane (DBCP) were studied by light and electron microscopy. In seven subjects, spermatogenic activity was either significantly decreased or absent. There appeared to be a correlation between the diminution in spermatogenesis and the duration of industrial exposure to the agent.