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Could the New BA.2.75 Sub-Variant Cause the Emergence of a Global Epidemic of COVID-19? A Scoping Review

Authors :
Nour Shaheen
Abdelrahman Mohamed
Almoatazbellah Attalla
Rehab Adel Diab
Sarya Swed
Abdulqadir J Nashwan
Ala’ Abdala Rababah
Mahmoud Tarek Hefnawy
Youssef Soliman
Omar Ahmed Abdelwahab
Mariam Tarek Desouki
Abdulrhman Khaity
Ahmed Shaheen
Abdelraouf Ramadan
Mostafa Meshref
Source :
Infection and Drug Resistance. 15:6317-6330
Publication Year :
2022
Publisher :
Informa UK Limited, 2022.

Abstract

With over 58 million cases and 6 million deaths by August 2022, the Coronavirus disease 2019 (COVID-19), causing severe acute respiratory syndrome coronavirus 2 (SARs-CoV-2), has had an insurmountable impact on the world's population. This is one of the worst health crises since 1918's influenza pandemic. There are four subvariants of Omicron; BA.1, BA.1.1, BA.2 and BA.3. As a result of new mutations in its spike protein, most of which occur in its receptor binding site, the Omicron variant appears to be more transmissible and less resistant to vaccination and antibody response. Understanding Omicron's virology and mutations is essential to developing diagnostic and therapeutic methods. A thorough assessment of control measures, as well as timely adjustment of control measures, requires addressing such issues as re-infection risk, vaccine response, booster vaccine doses, and the increased rate of Omicron infections. This review article aims to look at the current information about the different types of SARs-CoV-2, focusing on the new subtype BA.2.75.

Details

ISSN :
11786973
Volume :
15
Database :
OpenAIRE
Journal :
Infection and Drug Resistance
Accession number :
edsair.doi.dedup.....d051ceffcab1124c8c0ad9ab4510a482