ARYLSULPHATASE A (EC 3.1.6.1) ACTIVITY IN RAT CENTRAL NERVOUS SYSTEM DURING EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

— The activity of arylsulphatase A (EC 3.1.6.1) was measured in several brain sub cellular fractions during experimental allergic encephalomyelitis in rats. In the acute stage there was a slight but significant increase in the brain homogenate in comparison to that from control animals. The alteration appeared to be localized in a subcellular fraction con stituted mainly by myelin fragments. The arylsulphatase A activity returned to the control level in the recovery stage.