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Topical pharyngeal anesthesia provides no additional benefit to propofol sedation for esophagogastroduodenoscopy: a randomized controlled double-blinded clinical trial
- Source :
- Scientific Reports, Scientific Reports, Vol 8, Iss 1, Pp 1-5 (2018)
- Publication Year :
- 2018
- Publisher :
- Nature Publishing Group UK, 2018.
-
Abstract
- Propofol sedation has been applied during esophagogastroduodenoscopy procedures, but whether topical pharyngeal anesthesia should be administered at the same time has rarely been reported. Our study examined the role of topical pharyngeal anesthesia in sedated endoscopies in a randomized controlled double-blinded clinical trial. A total of 626 patients who underwent sedated esophagogastroduodenoscopy were randomized into the experimental group (n = 313) or the control group (n = 313). The discomfort score, immediately and one day after the procedure, was not statistically significant [7.2 (5–9) vs. 7.5 (6–9), P = 0.210; 2.3 (0–3) vs. 2.6 (0–4), P = 0.095, respectively]. Two patients in the experimental group and three patients in the control group needed oral medication for pharyngeal discomfort (P = 0.354). The satisfaction score was 9.2 (8–10) in the experimental group and 8.9 (7–10) in the control group (P = 0.778). Lidocaine topical pharyngeal anesthesia in propofol-sedated esophagogastroduodenoscopy did not further reduce the pharyngeal discomfort or improve the satisfaction. This clinical trial was registered at ClinicalTrials.gov (ClinicalTrials.gov ID: NCT03070379).
- Subjects :
- Adult
Male
Lidocaine
lcsh:Medicine
Propofol sedation
Article
law.invention
03 medical and health sciences
Young Adult
0302 clinical medicine
Randomized controlled trial
Double-Blind Method
030202 anesthesiology
Oral administration
law
medicine
Humans
Hypnotics and Sedatives
Anesthesia
Endoscopy, Digestive System
Young adult
lcsh:Science
Propofol
Multidisciplinary
medicine.diagnostic_test
Esophagogastroduodenoscopy
business.industry
lcsh:R
Middle Aged
Endoscopy
Clinical trial
Patient Outcome Assessment
lcsh:Q
030211 gastroenterology & hepatology
Female
business
Anesthetics, Intravenous
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 20452322 and 03070379
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....d12cdca73002eabb0504b88db899a46b