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Adalimumab-induced acute myeloid leukaemia in a patient with Crohn’s disease
- Source :
- BMJ Case Rep
- Publication Year :
- 2019
- Publisher :
- BMJ, 2019.
-
Abstract
- We present a patient with Crohn’s disease under treatment with adalimumab who developed acute myeloid leukaemia (AML) with core-binding factor beta gene rearrangement. This case report emphasises the importance of long-term close follow-up of patients receiving adalimumab because of the increased risk of developing AML and other malignancies.
- Subjects :
- Adult
Male
musculoskeletal diseases
Oncology
medicine.medical_specialty
Disease
Core Binding Factor beta Subunit
03 medical and health sciences
0302 clinical medicine
Crohn Disease
Bone Marrow
hemic and lymphatic diseases
Internal medicine
medicine
Adalimumab
Humans
Chemotherapy-Induced Febrile Neutropenia
skin and connective tissue diseases
Beta (finance)
Gene Rearrangement
030203 arthritis & rheumatology
Crohn's disease
Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions
business.industry
Remission Induction
Induction Chemotherapy
General Medicine
Gene rearrangement
medicine.disease
Consolidation Chemotherapy
Leukemia, Myeloid, Acute
Increased risk
Antirheumatic Agents
030211 gastroenterology & hepatology
Myeloid leukaemia
business
medicine.drug
Subjects
Details
- ISSN :
- 1757790X
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- BMJ Case Reports
- Accession number :
- edsair.doi.dedup.....d1367c6005c877812142752099bd076c
- Full Text :
- https://doi.org/10.1136/bcr-2018-225680