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Adalimumab-induced acute myeloid leukaemia in a patient with Crohn’s disease

Authors :
Talal Alzahrani
Nejat Naser
Amar R. Jariwala
Abdulelah Nuqali
Source :
BMJ Case Rep
Publication Year :
2019
Publisher :
BMJ, 2019.

Abstract

We present a patient with Crohn’s disease under treatment with adalimumab who developed acute myeloid leukaemia (AML) with core-binding factor beta gene rearrangement. This case report emphasises the importance of long-term close follow-up of patients receiving adalimumab because of the increased risk of developing AML and other malignancies.

Details

ISSN :
1757790X
Volume :
12
Database :
OpenAIRE
Journal :
BMJ Case Reports
Accession number :
edsair.doi.dedup.....d1367c6005c877812142752099bd076c
Full Text :
https://doi.org/10.1136/bcr-2018-225680