Activation of inflammatory pathways in PBMCs linking type 2 diabetes in older adults without obesity

Authors :: Hao-Chien Cheng
Shun-Hsi Tsai
Hung-Wen Liu
Source :: Experimental gerontology. 163
Publication Year :: 2021
Abstract: The mechanism that underlies the dysregulation of glucose metabolism in older adults without obesity has yet to be thoroughly understood. This study investigated the risk of developing Type 2 diabetes (T2D) in older adults without obesity (BMI: 18.5 to25 kg/m

Subjects :: Aging
Tumor Necrosis Factor-alpha
NF-kappa B
Cell Biology
Biochemistry
Prediabetic State
Endocrinology
Glucose
Diabetes Mellitus, Type 2
Sirtuin 1
Genetics
Leukocytes, Mononuclear
Humans
Obesity
Insulin Resistance
Molecular Biology
Aged

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