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Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: A Delphi consensus study in Europe

Authors :
Tiuri E. Kroese
Hanneke W.M. van Laarhoven
Sebastian F. Schoppman
Pieter R.A.J. Deseyne
Eric van Cutsem
Karin Haustermans
Philippe Nafteux
Melissa Thomas
Radka Obermannova
Hanna R. Mortensen
Marianne Nordsmark
Per Pfeiffer
Anneli Elme
Antoine Adenis
Guillaume Piessen
Christiane J. Bruns
Florian Lordick
Ines Gockel
Markus Moehler
Cihan Gani
Theodore Liakakos
John Reynolds
Alessio G. Morganti
Riccardo Rosati
Carlo Castoro
Francesco Cellini
Domenico D'Ugo
Franco Roviello
Maria Bencivenga
Giovanni de Manzoni
Mark I. van Berge Henegouwen
Maarten C.C.M. Hulshof
Jolanda van Dieren
Marieke Vollebergh
Johanna W. van Sandick
Paul Jeene
Christel T. Muijs
Marije Slingerland
Francine E.M. Voncken
Henk Hartgrink
Geert-Jan Creemers
Maurice J.C. van der Sangen
Grard Nieuwenhuijzen
Maaike Berbee
Marcel Verheij
Bas Wijnhoven
Laurens V. Beerepoot
Nadia H. Mohammad
Stella Mook
Jelle P. Ruurda
Piotr Kolodziejczyk
Wojciech P. Polkowski
Lucjan Wyrwicz
Maria Alsina
Manuel Pera
Tania F. Kanonnikoff
Andrés Cervantes
Magnus Nilsson
Stefan Monig
Anna D. Wagner
Matthias Guckenberger
Ewen A. Griffiths
Elizabeth Smyth
George B. Hanna
Sheraz Markar
M. Asif Chaudry
Maria A. Hawkins
Edward Cheong
Richard van Hillegersberg
Peter S.N. van Rossum
Tom Rozema
Joos Heisterkamp
Markus Schaefer
Esat-Mahmut Ozsahin
Jacco de Haan
Jan Willem van den Berg
Frederic Duprez
Eduard Callebout
Elke van Daele
Ulrich Hacker
Albrecht Hoffmeister
Thomas Kuhnt
Timm Denecke
Regine Kluge
Gerald Prager
A. Ilhan-Mutlu
Dajana Cuicchi
Andrea Ardizzoni
Camiel Rosman
Elske C. Gootjes
Heidi Rütten
Francesco Puccetti
Stefano Cascinu
Najla Slim
Maria Eugenia Barrios
Maria Carmen Fernandez
Roberto Martí-Oriol
Marisol Huerta Alvaro
Almudena Vera
Esther Jordá
Fernando L. Mozos
Anna Reig
Laura Visa
Bogumiła Ciseł
Joanna Czechowska
Magdalena Kwietniewska
Agnieszka Pikuła
Magdalena Skórzewska
Aleksandra Kozłowska
Karol Rawicz-Pruszyński
Internal medicine
Surgery
AII - Cancer immunology
CCA - Cancer biology and immunology
Radiation Oncology
Gastroenterology & Hepatology
Erasmus MC other
Institut Català de la Salut
[Kroese TE] Department of Surgery, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands. Department of Radiation Oncology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands. [van Laarhoven HWM] Amsterdam UMC Location University of Amsterdam, Department of Medical Oncology, Amsterdam, the Netherlands. Cancer Center Amsterdam, Cancer Treatment and Quality of Life, Amsterdam, the Netherlands. [Schoppman SF] Department of Surgery, Medical University of Vienna, Vienna University, Vienna, Austria. [Deseyne PRAJ] Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium. [van Cutsem E] Department of Medical Oncology, KU Leuven, Leuven University, Leuven, Belgium. [Haustermans K] Department of Radiation Oncology, KU Leuven, Leuven University, Leuven, Belgium. [Alsina M] Servei d’Oncologia Mèdica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain
Vall d'Hebron Barcelona Hospital Campus
Source :
European Journal of Cancer, 185, pp. 28-39, European Journal of Cancer, 185, 28-39. Pergamon, European Journal of Cancer, 185, 28-39. Elsevier Ltd., Scientia, European Journal of Cancer, 185, 28-39, Kroese, T E, van Laarhoven, H W M, Schoppman, S F, Deseyne, P R A J, van Cutsem, E, Haustermans, K, Nafteux, P, Thomas, M, Obermannova, R, Mortensen, H R, Nordsmark, M, Pfeiffer, P, Elme, A, Adenis, A, Piessen, G, Bruns, C J, Lordick, F, Gockel, I, Moehler, M, Gani, C, Liakakos, T, Reynolds, J, Morganti, A G, Rosati, R, Castoro, C, Cellini, F, D'Ugo, D, Roviello, F, Bencivenga, M, de Manzoni, G, van Berge Henegouwen, M I, Hulshof, M C C M, van Dieren, J, Vollebergh, M, van Sandick, J W, Jeene, P, Muijs, C T, Slingerland, M, Voncken, F E M, Hartgrink, H, Creemers, G J, van der Sangen, M J C, Nieuwenhuijzen, G, Berbee, M, Verheij, M, Wijnhoven, B, Beerepoot, L V, Mohammad, N H, Mook, S, Ruurda, J P & the OMEC collaborators 2023, ' Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer : A Delphi consensus study in Europe ', European Journal of Cancer, vol. 185, pp. 28-39 . https://doi.org/10.1016/j.ejca.2023.02.015, the OMEC collaborators 2023, ' Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer : A Delphi consensus study in Europe ', European Journal of Cancer, vol. 185, pp. 28-39 . https://doi.org/10.1016/j.ejca.2023.02.015
Publication Year :
2023

Abstract

Gastric cancer; Metastasectomy; Oligometastasis Cáncer gástrico; Metastasectomía; Oligometástasis Càncer gàstric; Metastasectomia; Oligometàstasi Background Local treatment improves the outcomes for oligometastatic disease (OMD, i.e. an intermediate state between locoregional and widespread disseminated disease). However, consensus about the definition, diagnosis and treatment of oligometastatic oesophagogastric cancer is lacking. The aim of this study was to develop a multidisciplinary European consensus statement on the definition, diagnosis and treatment of oligometastatic oesophagogastric cancer. Methods In total, 65 specialists in the multidisciplinary treatment for oesophagogastric cancer from 49 expert centres across 16 European countries were requested to participate in this Delphi study. The consensus finding process consisted of a starting meeting, 2 online Delphi questionnaire rounds and an online consensus meeting. Input for Delphi questionnaires consisted of (1) a systematic review on definitions of oligometastatic oesophagogastric cancer and (2) a discussion of real-life clinical cases by multidisciplinary teams. Experts were asked to score each statement on a 5-point Likert scale. The agreement was scored to be either absent/poor (2 years, either upfront local treatment or systemic treatment followed by restaging was considered as treatment (fair agreement). Conclusion The OMEC project has resulted in a multidisciplinary European consensus statement for the definition, diagnosis and treatment of oligometastatic oesophagogastric adenocarcinoma and squamous cell cancer. This can be used to standardise inclusion criteria for future clinical trials.

Details

ISSN :
09598049
Database :
OpenAIRE
Journal :
European Journal of Cancer, 185, pp. 28-39, European Journal of Cancer, 185, 28-39. Pergamon, European Journal of Cancer, 185, 28-39. Elsevier Ltd., Scientia, European Journal of Cancer, 185, 28-39, Kroese, T E, van Laarhoven, H W M, Schoppman, S F, Deseyne, P R A J, van Cutsem, E, Haustermans, K, Nafteux, P, Thomas, M, Obermannova, R, Mortensen, H R, Nordsmark, M, Pfeiffer, P, Elme, A, Adenis, A, Piessen, G, Bruns, C J, Lordick, F, Gockel, I, Moehler, M, Gani, C, Liakakos, T, Reynolds, J, Morganti, A G, Rosati, R, Castoro, C, Cellini, F, D'Ugo, D, Roviello, F, Bencivenga, M, de Manzoni, G, van Berge Henegouwen, M I, Hulshof, M C C M, van Dieren, J, Vollebergh, M, van Sandick, J W, Jeene, P, Muijs, C T, Slingerland, M, Voncken, F E M, Hartgrink, H, Creemers, G J, van der Sangen, M J C, Nieuwenhuijzen, G, Berbee, M, Verheij, M, Wijnhoven, B, Beerepoot, L V, Mohammad, N H, Mook, S, Ruurda, J P & the OMEC collaborators 2023, ' Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer : A Delphi consensus study in Europe ', European Journal of Cancer, vol. 185, pp. 28-39 . https://doi.org/10.1016/j.ejca.2023.02.015, the OMEC collaborators 2023, ' Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer : A Delphi consensus study in Europe ', European Journal of Cancer, vol. 185, pp. 28-39 . https://doi.org/10.1016/j.ejca.2023.02.015
Accession number :
edsair.doi.dedup.....d1b20a8356697ebf5794c5856945e14a
Full Text :
https://doi.org/10.1016/j.ejca.2023.02.015