Back to Search
Start Over
Suubi+Adherence-Round 2: A study protocol to examine the longitudinal HIV treatment adherence among youth living with HIV transitioning into young adulthood in Southern Uganda
- Source :
- BMC Public Health, BMC Public Health, Vol 21, Iss 1, Pp 1-21 (2021)
- Publication Year :
- 2021
- Publisher :
- Columbia University, 2021.
-
Abstract
- BackgroundYouth living with HIV (YLHIV) in Sub-Saharan African (SSA) are less likely to adhere to antiretroviral therapy (ART) and other health-related regimens. As a consequence, YLHIV are not only at risk for health problems and mental health comorbidities, but are also at risk for cognitive deficits, including in areas of memory and executive functioning. The Suubi+Adherence study followed 702 adolescents (10-16 years of age) receiving bolstered standard of care and a family economic empowerment intervention comprising an incentivized youth financial savings account (YSA) augmented with financial literacy training (FLT) and peer mentorship. The study findings pointed to superior short-term viral suppression and positive adolescent health and mental health functioning among participants receiving the intervention. The original group of adolescents who received Suubi+Adherence are now transitioning into young adulthood. This paper presents a protocol for the follow-up phase titled Suubi+Adherence Round 2.MethodsThe original cohort in Suubi+Adherence will be tracked for an additional five years (2020-2025). Specifically, the long term follow-up will allow to: 1) ascertain the extent to which the short term outcomes identified in the first 6 years of the intervention are maintained as the same group transitions through young adulthood; and 2) address new scientific questions regarding ART adherence; HIV care engagement; protective health behaviors; and the potential of FEE to mitigate the development of HIV-associated neurocognitive disorders in YLHIV. Additionally, the team examines the potential mechanisms through which the observed long-term outcomes happen. Moreover, the Suubi+Adherence-Round 2 adds a qualitative component and extends the cost effectiveness component.DiscussionGuided by asset and human development theories, Suubi+Adherence-R2 will build on the recently concluded Suubi+Adherence study to conduct one of the largest and longest running studies of YLHIV in SSA as they transition into young adulthood. The study will address new scientific questions regarding long-term ART adherence, HIV care engagement, protective health behaviors, and the potential of FEE to mitigate the development of HIV-associated neurocognitive disorders in YLHIV. The findings may inform efforts to improve HIV care among Uganda’s YLHIV, with potential replicability in other low-resource countries.Trial registrationClinicalTrials.gov, ID:NCT01790373
- Subjects :
- Gerontology
Adult
sub-Saharan Africa
medicine.medical_specialty
Adolescent
Cost effectiveness
Adolescent Health
HIV Infections
Medication Adherence
03 medical and health sciences
Young Adult
Study Protocol
0302 clinical medicine
Acquired immunodeficiency syndrome (AIDS)
Intervention (counseling)
Medicine
Humans
Uganda
030212 general & internal medicine
Young adult
economic empowerment
030505 public health
business.industry
lcsh:Public aspects of medicine
Public health
Public Health, Environmental and Occupational Health
lcsh:RA1-1270
Youth living with HIV
cohort
medicine.disease
Mental health
Treatment Adherence and Compliance
HIV/AIDS
0305 other medical science
business
Neurocognitive
Adolescent health
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- BMC Public Health, BMC Public Health, Vol 21, Iss 1, Pp 1-21 (2021)
- Accession number :
- edsair.doi.dedup.....d1d5dfabae6cd75e5ed9af361d2cfe12
- Full Text :
- https://doi.org/10.7916/k47r-tv67