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P616Cardioprotective effects of nanoemulsions loaded with natural anti-inflammatory molecules against doxorubicin-induced cardiotoxicity in cardiomyocytes

Authors :
C Di Cicco
Paolo A. Netti
Giovanna Piscopo
C. Coppola
Nicola Maurea
Rosario Vincenz Iaffaioli
Rolando Paciello
Gerardo Botti
A. De Capua
Vincenzo Quagliariello
Raffaele Vecchione
Luscher TF
Maurea, N
Quagliariello, V
Vecchione, R
Di Cicco, C
De Capua, A
Coppola, C
Piscopo, G
Paciello, R
Iaffaioli, Rv
Netti, Pa
Botti, G
Publication Year :
2018

Abstract

Cardiotoxicity is one of the most significant adverse effects of the oncologic treatment with doxorubicin, which is responsible for a substantial morbid and mortality. Small molecules derived from medicinal plants with anti-inflammatory properties could have cardioprotective activites so potentially used in cardio-oncology management. Nanomedicine offer a new pharmacological tool able to increase bioavailability and protect natural bioactives with antiinflammatory and cardioprotective action.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....d24e6c2e12f8f69673c6151e3cf73304