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Cell transplantation for treatment of left-ventricular dysfunction due to ischemic heart failure: from bench to bedside
- Source :
- Expert Review of Cardiovascular Therapy. 5:125-131
- Publication Year :
- 2007
- Publisher :
- Informa UK Limited, 2007.
-
Abstract
- Cell transplantation is an innovative technology that involves the implantation of a variety of myogenic and angiogenic cell types. The transplanted cells proliferate and augment left ventricular performance and therein ameliorate the heart failure symptoms. The concept of cell transplantation has followed the footsteps of angiogenesis starting as bench side research. The latter half of the decade saw the transformation of this potential mechanism to a promising therapy for ischemic heart failure. More than 150 patients have been treated with cellular transplantation worldwide. This novel application has the potential to revolultionalize alternative therapeutic approaches to management of heart failure.
- Subjects :
- Cardiac Catheterization
medicine.medical_specialty
Cell type
Cell Survival
Cell Transplantation
Angiogenesis
Cell Culture Techniques
Myocardial Ischemia
Neovascularization, Physiologic
Electrocardiography
Ventricular Dysfunction, Left
Cell transplantation
Internal medicine
Internal Medicine
medicine
Animals
Humans
Myocytes, Cardiac
Myocardial infarction
Potential mechanism
Bone Marrow Transplantation
Ventricular Remodeling
business.industry
Recovery of Function
General Medicine
medicine.disease
Bench to bedside
Heart failure
Cardiology
Electrophysiologic Techniques, Cardiac
Cardiology and Cardiovascular Medicine
business
Ischemic heart
Stem Cell Transplantation
Subjects
Details
- ISSN :
- 17448344 and 14779072
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Expert Review of Cardiovascular Therapy
- Accession number :
- edsair.doi.dedup.....d26d233baac7212f7d435ced724ca49b