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Safety Update

Authors :
R. Scott Wright
Jonathon W. Senefeld
Brian P. Butterfield
Joshua J. Dennis
Elizabeth R. Lesser
Juan C. Diaz Soto
Chad C. Wiggins
Katie L. Kunze
Robert F. Rea
Matthew A. Sexton
Patrick W. Johnson
Peter W. Marks
Emily R. Whelan
Jeffrey L. Winters
Kathryn F. Larson
Nicole C. Verdun
Andrew J. Clayburn
Riley J. Regimbal
Matthew R. Spiegel
Matthew N.P. Vogt
Janis E. Blair
Philippe R. Bauer
Sarah E. Baker
Allan M. Klompas
Nigel Paneth
David O. Hodge
Noud van Helmond
Vitaly Herasevich
Michael J. Joyner
De Lisa Fairweather
John R. A. Shepherd
James R. Stubbs
Matthew R. Buras
Rickey E. Carter
Camille M. van Buskirk
Kylie J. Andersen
Arturo Casadevall
Juan G. Ripoll
Katelyn A. Bruno
Stephen A. Klassen
Source :
Mayo Clinic Proceedings
Publication Year :
2020
Publisher :
Elsevier BV, 2020.

Abstract

OBJECTIVE: To provide an update on key safety metrics after transfusion of convalescent plasma in hospitalized coronavirus 2019 (COVID-19) patients, having previously demonstrated safety in 5000 hospitalized patients. PATIENTS AND METHODS: From April 3 to June 2, 2020, the US Food and Drug Administration Expanded Access Program for COVID-19 convalescent plasma transfused a convenience sample of 20,000 hospitalized patients with COVID-19 convalescent plasma. RESULTS: The incidence of all serious adverse events was low; these included transfusion reactions (n=78

Details

ISSN :
00256196
Volume :
95
Database :
OpenAIRE
Journal :
Mayo Clinic Proceedings
Accession number :
edsair.doi.dedup.....d27178ec62485317c91b2eeda5ff8610