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Trends in virological and clinical outcomes in individuals with HIV-1 infection and virological failure of drugs from three antiretroviral drug classes: a cohort study

Authors :
Castagliola, D
Ledergerber, B
Torti, Carlo
van Sighem, A
Podzamczer, D
Mocroft, A
Dorrucci, M
Masquelier, B
de Luca, A
Jansen, K
De Wit, S
Obel, N
Fätkenheuer, G
Touloumi, G
Mussini, C
Castagna, A
Stephan, C
Garcia, F
Zangerle, R
Duval, X
Pérez Hoyos, S
Meyer, L
Ghosn, J
Fabre Colin, C
Kjaer, J
Chene, G
Grarup, J
Costagliola, D
Lodwick, R
Phillips, A
Pursuing Later Treatment Option II project team
Observational HIV Epidemiological Research Europe Group
Costagliola
D, Lodwick
R, Ledergerber
B, Collaboration Of Observational Hiv Epidemiological Research Europe (COHERE) Grp
Castagna, Antonella
Other departments
AII - Amsterdam institute for Infection and Immunity
APH - Amsterdam Public Health
Global Health
Infectious diseases
Source :
Lancet. Infectious diseases, 12 (2, The Lancet Infectious Diseases; Vol 12, Lancet infectious diseases, 12(2), 119-127. Lancet Publishing Group
Publication Year :
2012

Abstract

Limited treatment options have been available for people with HIV who have had virological failure of the three original classes of HIV antiretroviral drugs-so-called triple-class virological failure (TCVF). However, introduction of new drugs and drug classes might have improved outcomes. We aimed to assess trends in virological and clinical outcomes for individuals with TCVF in 2000-09.<br />info:eu-repo/semantics/published

Details

ISSN :
14733099
Database :
OpenAIRE
Journal :
Lancet. Infectious diseases, 12 (2, The Lancet Infectious Diseases; Vol 12, Lancet infectious diseases, 12(2), 119-127. Lancet Publishing Group
Accession number :
edsair.doi.dedup.....d28a083f904fe9e84136c99522107ac2