Video 3 from CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies

Supplemental Video 3. In vitro visualization of the dynamics of CD20-TCB (white) during interaction between CD8+ T-cells (green) and tumor cells (blue). The video focuses on an example of CD20-TCB-mediated CD8+ T-cell cytotoxicity of tumor cells. T-cells surround the tumor cells and create stable synapses where CD20-TCB is localized (white). Tumor cells are killed upon certain time of T-cell/tumor cell interaction as evidenced by the formation of tumor blebs.