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Increased Regional Deformation of the Left Ventricle in Normal Children With Increased Body Mass Index: Implications for Future Cardiovascular Health
- Source :
- Pediatric Cardiology. 35:315-322
- Publication Year :
- 2013
- Publisher :
- Springer Science and Business Media LLC, 2013.
-
Abstract
- The prevalence of obesity continues to increase in the developing world. The effects of obesity on the cardiovascular system include changes in systolic and diastolic function. More recently obesity has been linked with impairment of longitudinal myocardial deformation properties in children. We sought to determine the effect of increased body mass index (BMI) on cardiac deformation in a group of children taking part in the population-based Southampton Women’s Survey to detect early cardiovascular changes associated with increasing BMI before established obesity. Sixty-eight children at a mean age of 9.4 years old underwent assessment of longitudinal myocardial deformation in the basal septal segment of the left ventricle (LV) using two-dimensional speckle tracking echocardiography. Parameters of afterload and preload, which may influence deformation, were determined from cardiac magnetic resonance imaging. BMI was determined from the child’s height and weight at the time of echocardiogram. Greater pediatric BMI was associated with greater longitudinal myocardial deformation or strain in the basal septal segment of the LV (β = 1.6, p
- Subjects :
- Male
medicine.medical_specialty
Heart Ventricles
Population
Magnetic Resonance Imaging, Cine
Aorta, Thoracic
Speckle tracking echocardiography
Body Mass Index
Contractility
Afterload
Reference Values
Risk Factors
Cardiac magnetic resonance imaging
Internal medicine
medicine
Humans
Ventricular Function
Obesity
Child
education
education.field_of_study
medicine.diagnostic_test
business.industry
Incidence
Reproducibility of Results
United Kingdom
Preload
medicine.anatomical_structure
Cardiovascular Diseases
Echocardiography
Ventricle
Pediatrics, Perinatology and Child Health
Cardiology
Female
Cardiology and Cardiovascular Medicine
business
Body mass index
Follow-Up Studies
Subjects
Details
- ISSN :
- 14321971 and 01720643
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- Pediatric Cardiology
- Accession number :
- edsair.doi.dedup.....d32db1f6f06a05278cd242df417f1ad5