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Identifying the optimal candidates for locoregional radiation therapy in patients with de novo metastatic nasopharyngeal carcinoma
- Source :
- Head & Neck. 43:2602-2610
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- BACKGROUND To evaluate the value of locoregional radiation therapy (LRRT) in de novo metastatic nasopharyngeal carcinoma (mNPC) and identify suitable candidates for additional LRRT after palliative chemotherapy (PCT). METHODS Patients with de novo mNPC received platinum-based chemotherapy for a minimum of four cycles with or without definitive LRRT via intensity-modulated radiation therapy (IMRT) were all candidates for this study. RESULTS A total of 168 patients were included for this analysis. Additional LRRT was associated with significantly longer median OS (69.5 vs. 17.8 months, p
- Subjects :
- 0301 basic medicine
Oncology
medicine.medical_specialty
medicine.medical_treatment
Disease
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
Humans
In patient
Retrospective Studies
Chemotherapy
Nasopharyngeal Carcinoma
business.industry
Palliative Care
Nasopharyngeal Neoplasms
Palliative chemotherapy
Immunotherapy
medicine.disease
Radiation therapy
030104 developmental biology
Survival benefit
Otorhinolaryngology
Nasopharyngeal carcinoma
030220 oncology & carcinogenesis
Radiotherapy, Intensity-Modulated
business
Subjects
Details
- ISSN :
- 10970347 and 10433074
- Volume :
- 43
- Database :
- OpenAIRE
- Journal :
- Head & Neck
- Accession number :
- edsair.doi.dedup.....d338fa30772bfe4b32a996af2d86f3de