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Exosome-Encased Nucleic Acid Scaffold Chemotherapeutic Agents for Superior Anti-Tumor and Anti-Angiogenesis Activity
Exosome-Encased Nucleic Acid Scaffold Chemotherapeutic Agents for Superior Anti-Tumor and Anti-Angiogenesis Activity
- Source :
- ACS Bio & Med Chem Au. 2:140-149
- Publication Year :
- 2022
- Publisher :
- American Chemical Society (ACS), 2022.
-
Abstract
- Extracellular vesicles (EVs), or exosomes, play a pivotal role in tumor growth and metastasis, such as in the case of Kaposi Sarcoma. By loading tumor-derived EVs with chemotherapeutic drugs, we noted that their pro-tumor/pro-angiogenic phenotype was converted into an anti-tumor phenotype
- Subjects :
- Drug Discovery
Pharmaceutical Science
Molecular Biology
Biochemistry
Subjects
Details
- ISSN :
- 26942437
- Volume :
- 2
- Database :
- OpenAIRE
- Journal :
- ACS Bio & Med Chem Au
- Accession number :
- edsair.doi.dedup.....d34cb7adef4de9158f22a51422971d2d
- Full Text :
- https://doi.org/10.1021/acsbiomedchemau.1c00030