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Kidney Transplantation after Rescue Allocation - The Eurotransplant Experience
- Source :
- Transplantation, 106(6), 1215-1226. Lippincott Williams & Wilkins, Transplantation, 106(6), 1215-1226. LIPPINCOTT WILLIAMS & WILKINS, Transplantation, 106(6), 1215-1226. Lippincott Williams and Wilkins, Assfalg, V, Miller, G, Stocker, F, van Meel, M, Groenevelt, T, Tieken, I, Ankerst, D, Renders, L, Novotny, A, Hartmann, D, Jell, A, Rahmel, A, Wahba, R, Mühlfeld, A, Bouts, A, Ysebaert, D, Globke, B, Jacobs-Tulleneers-Thevissen, D, Piros, L S, Stippel, D, Heller, K, Eisenberger, U, van Laecke, S, Weimer, R, Rosenkranz, A R, Berger, S, Fischer, L, Kliem, V, Vondran, F, Sester, U, Schneeberger, S, Harth, A, Kuypers, D, Függer, R, Arnol, M, Christiaans, M, Weinmann-Menke, J, Krüger, B, Hilbrands, L, Banas, B, Hakenberg, O, Minnee, R, Schwenger, V, Heyne, N, van Zuilen, A, Reindl-Schwaighofer, R, Lopau, K, Huser, N & Heemann, U 2022, ' Kidney Transplantation after Rescue Allocation-The Eurotransplant Experience : A Retrospective Multicenter Outcome Analysis ', Transplantation, vol. 106, no. 6, pp. 1215-1226 . https://doi.org/10.1097/TP.0000000000003964, Transplantation, 106, 1215-1226, TRANSPLANTATION, Transplantation, 106, 6, pp. 1215-1226, Transplantation
- Publication Year :
- 2022
- Publisher :
- Lippincott Williams & Wilkins, 2022.
-
Abstract
- BACKGROUND: At Eurotransplant (ET), kidneys are transferred to "rescue allocation" (RA), whenever the standard allocation (SA) algorithms Eurotransplant Kidney Allocation System (ETKAS) and Eurotransplant Senior Program (ESP) fail. We analyzed the outcome of RA. METHODS: Retrospective patient clinical and demographic characteristics association analyses were performed with graft outcomes for 2422 recipients of a deceased donor renal transplantation (DDRT) after RA versus 25 481 after SA from 71 centers across all ET countries from 2006 to 2018. RESULTS: Numbers of DDRTs after RA increased over the time, especially in Germany. RA played a minor role in ESP versus ETKAS (2.7% versus 10.4%). RA recipients and donors were older compared with SA recipients and donors, cold ischemia times were longer, waiting times were shorter, and the incidence of primary nonfunction was comparable. Among ETKAS recipients, HLA matching was more favorable in SA (mean 3.7 versus 2.5). In multivariate modeling, the incidence of graft loss in ETKAS recipients was reduced in RA compared with SA (subdistribution hazard ratio, 0.80; 95% confidence interval [0.70-0.91], P
- Subjects :
- Waiting time
kidney
PREDICTOR
medicine.medical_specialty
Tissue and Organ Procurement
Eurotransplant
medicine.medical_treatment
Medizin
Outcome analysis
deceased donor renal transplantation
COLD ISCHEMIA TIME
surgery
All institutes and research themes of the Radboud University Medical Center
Internal medicine
DIALYSIS
Medicine and Health Sciences
Humans
Medicine
standard allocation
FRAILTY
Kidney transplantation
Dialysis
Retrospective Studies
RISK
GRAFT FAILURE
Transplantation
Deceased donor
rescue allocation
business.industry
MORTALITY
Incidence (epidemiology)
Graft Survival
algorithms Eurotransplant kidney allocation system
ASSOCIATION
medicine.disease
Kidney Transplantation
Tissue Donors
Confidence interval
Eurotransplant senior program
RECIPIENTS
Treatment Outcome
SURVIVAL
Human medicine
Renal disorders Radboud Institute for Health Sciences [Radboudumc 11]
business
Subjects
Details
- Language :
- English
- ISSN :
- 15346080 and 00411337
- Volume :
- 106
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Transplantation
- Accession number :
- edsair.doi.dedup.....d38a94959cc49968018634954373a919