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Combined impacts of low apolipoprotein A-I levels and reduced renal function on long-term prognosis in patients with coronary artery disease undergoing percutaneous coronary intervention

Authors :
Tatsuya Fukase
Tomotaka Dohi
Ryota Nishio
Mitsuhiro Takeuchi
Norihito Takahashi
Yuichi Chikata
Hirohisa Endo
Shinichiro Doi
Hiroki Nishiyama
Iwao Okai
Hiroshi Iwata
Shinya Okazaki
Katsumi Miyauchi
Hiroyuki Daida
Tohru Minamino
Source :
Clinica chimica acta; international journal of clinical chemistry. 536
Publication Year :
2022

Abstract

The relationship of apolipoprotein A-I (ApoA-I) and renal function in patients after intervention remain unclear, thus, we aimed to evaluate the combined impacts of ApoA-I and kidney disease (KAltogether, 4101 consecutive patients who underwent intervention between 2000 and 2016 were included. The patients were divided into four groups based on the median ApoA-I values and presence of KDuring the median follow-up period of 6.2 years, 618 patients (15.1%) developed MACCE, and 627 patients (15.3%) died. ApoA-I level was significantly related to estimated glomerular filtration rate, and ApoA-I levels and KThe combined impacts of ApoA-I and renal function could be useful for evaluating cardiovascular and life prognoses in patients undergoing intervention.

Details

ISSN :
18733492
Volume :
536
Database :
OpenAIRE
Journal :
Clinica chimica acta; international journal of clinical chemistry
Accession number :
edsair.doi.dedup.....d3efd089abe9e1ad7f9e824c0396a101