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Comparison of screening strategies with two new tests to score and diagnose varices needing treatment
- Source :
- Calès, Paul; Ravaioli, Federico; Berger, Arthur; Farcau, Oana; Festi, Davide; Stefanescu, Horia; Vitellius, Carole; Nahon, Pierre; Bureau, Christophe; Ganne-Carriè, Nathalie; Berzigotti, Annalisa; de Ledinghen, Victor; Petta, Salvatore (2022). Comparison of screening strategies with two new tests to score and diagnose varices needing treatment. Clinics and research in hepatology and gastroenterology, 46(7), p. 101925. Elsevier Masson 10.1016/j.clinre.2022.101925
- Publication Year :
- 2022
-
Abstract
- Background and aims: We aimed to improve non-invasive screening of varices needing treatment (VNT) and compare different screening strategies. Methods: 2,290 patients with chronic liver disease were included in a retrospective study. Etiologies were: virus: 50.0%, NAFLD: 29.5%, alcohol: 20.5%, VNT: 14.9%. Test descriptors were performance (spared endoscopy) and safety (missed VNT). VNT tests were evaluated according to their safety levels either for individual screening (95% negative predictive value (NPV)), population screening (95% sensitivity) or undifferentiated screening (100% sensitivity/NPV) without missed VNT. The tests provided three categories: missed VNT
Details
- ISSN :
- 2210741X
- Volume :
- 46
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Clinics and research in hepatology and gastroenterology
- Accession number :
- edsair.doi.dedup.....d445c80e114b229005856700368ca1d0
- Full Text :
- https://doi.org/10.1016/j.clinre.2022.101925