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Prevalence of Ipsilateral Nonstenotic Carotid Plaques on Computed Tomography Angiography in Embolic Stroke of Undetermined Source
- Source :
- Stroke. 51(6)
- Publication Year :
- 2020
-
Abstract
- Background and Purpose— Embolic stroke of undetermined source (ESUS) constitutes a large proportion of acute ischemic stroke. It is crucial to identify possible stroke etiologies in this patient subgroup to individually tailor secondary stroke prevention strategies. This study aimed to assess the prevalence of carotid plaques causing Methods— Patients from INTERRSeCT—a multicenter prospective study of patients with acute ischemic stroke—were included in this study if their stroke etiology was not large artery atherosclerosis (>50% stenosis), and neck computed tomography angiography was obtained. Degree of stenosis ( Results— Four hundred forty-six patients were included in the study (median age, 73 years; 218 men), 138 of which were ESUS patients (median age, 70 years; 61 men). Nonstenotic carotid plaques (with P =0.004). Nonstenotic carotid plaques were significantly associated with ipsilateral strokes (adjusted odds ratio, 1.83 [95% CI, 1.05–3.18]). Conclusions— In patients with ESUS, nonstenotic carotid plaques were significantly more common on the side of the ischemic stroke, suggesting that these plaques could be a potential stroke etiology in patients in whom the ischemic stroke is classified currently as ESUS.
- Subjects :
- Carotid Artery Diseases
Male
medicine.medical_specialty
Computed Tomography Angiography
Embolism
030204 cardiovascular system & hematology
Brain Ischemia
03 medical and health sciences
0302 clinical medicine
Internal medicine
Prevalence
Medicine
Humans
cardiovascular diseases
Prospective Studies
Vascular Calcification
Acute ischemic stroke
Stroke
Computed tomography angiography
Aged
Advanced and Specialized Nursing
Aged, 80 and over
medicine.diagnostic_test
business.industry
Middle Aged
medicine.disease
Plaque, Atherosclerotic
Embolic stroke
Cryptogenic stroke
Cardiology
Etiology
Female
Neurology (clinical)
Cardiology and Cardiovascular Medicine
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 15244628
- Volume :
- 51
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Stroke
- Accession number :
- edsair.doi.dedup.....d4522ae2716d6d2a97e9319b0ea5cd97